Randomised controlled study investigating standard dose continuous renal replacement therapy (CRRT) versus low-dose CRRT in critically ill patients with acute kidney injury (AKI): study protocol for a prospective, randomised, controlled, international, multicentre trial (the ‘Ketzerei’ trial)

Christian Strauß, Mahan Sadjadi, Thilo von Groote, Hendrik Booke, Ludwig Maximilian Schöne, Clara Hegner, Carola Wempe, Melanie Meersch, Joachim Gerss, Alice Bernard, Helene Anna Haeberle, Peter Rosenberger, Tim Rahmel, Matthias Unterberg, Michael Adamzik, Christian Arndt, Hinnerk Wulf, Stefano Romagnoli, Manuela Bonizzoli, Raffaele Mandarano, Vedran Premuzic, Lucia Andrade, Igor Smolentzov, Sean M Bagshaw, Lakhmir Chawla, Alexander Zarbock

Open source

DOI: 10.1136/bmjopen-2025-105459
Published: 2025-09
Container: BMJ Open
Publisher: BMJ
Open access: unknown

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Cite this work

BibTeX

@article{allodium:10.1136/bmjopen-2025-105459,
  title = {Randomised controlled study investigating standard dose continuous renal replacement therapy (CRRT) versus low-dose CRRT in critically ill patients with acute kidney injury (AKI): study protocol for a prospective, randomised, controlled, international, multicentre trial (the ‘Ketzerei’ trial)},
  author = {Christian Strauß and Mahan Sadjadi and Thilo von Groote and Hendrik Booke and Ludwig Maximilian Schöne and Clara Hegner and Carola Wempe and Melanie Meersch and Joachim Gerss and Alice Bernard and Helene Anna Haeberle and Peter Rosenberger and Tim Rahmel and Matthias Unterberg and Michael Adamzik and Christian Arndt and Hinnerk Wulf and Stefano Romagnoli and Manuela Bonizzoli and Raffaele Mandarano and Vedran Premuzic and Lucia Andrade and Igor Smolentzov and Sean M Bagshaw and Lakhmir Chawla and Alexander Zarbock},
  year = {2025},
  journal = {BMJ Open},
  doi = {10.1136/bmjopen-2025-105459},
  url = {https://doi.org/10.1136/bmjopen-2025-105459}
}

RIS

TY  - JOUR
TI  - Randomised controlled study investigating standard dose continuous renal replacement therapy (CRRT) versus low-dose CRRT in critically ill patients with acute kidney injury (AKI): study protocol for a prospective, randomised, controlled, international, multicentre trial (the ‘Ketzerei’ trial)
AU  - Christian Strauß
AU  - Mahan Sadjadi
AU  - Thilo von Groote
AU  - Hendrik Booke
AU  - Ludwig Maximilian Schöne
AU  - Clara Hegner
AU  - Carola Wempe
AU  - Melanie Meersch
AU  - Joachim Gerss
AU  - Alice Bernard
AU  - Helene Anna Haeberle
AU  - Peter Rosenberger
AU  - Tim Rahmel
AU  - Matthias Unterberg
AU  - Michael Adamzik
AU  - Christian Arndt
AU  - Hinnerk Wulf
AU  - Stefano Romagnoli
AU  - Manuela Bonizzoli
AU  - Raffaele Mandarano
AU  - Vedran Premuzic
AU  - Lucia Andrade
AU  - Igor Smolentzov
AU  - Sean M Bagshaw
AU  - Lakhmir Chawla
AU  - Alexander Zarbock
PY  - 2025
JO  - BMJ Open
DO  - 10.1136/bmjopen-2025-105459
UR  - https://doi.org/10.1136/bmjopen-2025-105459
ER  -

APA

Strauß, C., Sadjadi, M., Groote, T. V., Booke, H., Schöne, L. M., Hegner, C., Wempe, C., Meersch, M., Gerss, J., Bernard, A., Haeberle, H. A., Rosenberger, P., Rahmel, T., Unterberg, M., Adamzik, M., Arndt, C., Wulf, H., Romagnoli, S., Bonizzoli, M., Mandarano, R., Premuzic, V., Andrade, L., Smolentzov, I., Bagshaw, S. M., Chawla, L., & Zarbock, A. (2025). Randomised controlled study investigating standard dose continuous renal replacement therapy (CRRT) versus low-dose CRRT in critically ill patients with acute kidney injury (AKI): study protocol for a prospective, randomised, controlled, international, multicentre trial (the ‘Ketzerei’ trial). BMJ Open. https://doi.org/10.1136/bmjopen-2025-105459

Source records

crossref · retrieved 2026-09-26T13:52:14.588Z