Multicentre, controlled, randomised and single-blind, adaptive phase IV protocol to evaluate effectiveness and cost-effectiveness of a pre-emptive genotyping strategy to optimise tacrolimus dosage in a pretransplant chronic kidney disease population cohort: iPHARMGx TRANSPGx nested clinical trial

Enrique Seco-Meseguer, Stefan Stewart, Elena Diago-Sempere, Carlos Jiménez, Nicolas Macías Carmona, Juan Fernández Solís, Anna Vila Santandreu, Rosalía Valero San Cecilio, Verónica López Jiménez, Montserrat Carmona-Rodríguez, Luis A López-Fernández, Iñaki Imaz-Iglesia, María del Mar García-Saiz, Magí Farré, Consuelo Rodriguez-Jimenez, Judith Sanabria-Cabrera, Rocío Rosas-Alonso, Irene García-García, Alberto M Borobia

Open source

DOI
10.1136/bmjopen-2025-109279
Published
2026-08
Container
BMJ Open
Publisher
BMJ
Open access
unknown

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BibTeX

@article{allodium:10.1136/bmjopen-2025-109279,
  title = {Multicentre, controlled, randomised and single-blind, adaptive phase IV protocol to evaluate effectiveness and cost-effectiveness of a pre-emptive genotyping strategy to optimise tacrolimus dosage in a pretransplant chronic kidney disease population cohort: iPHARMGx TRANSPGx nested clinical trial},
  author = {Enrique Seco-Meseguer and Stefan Stewart and Elena Diago-Sempere and Carlos Jiménez and Nicolas Macías Carmona and Juan Fernández Solís and Anna Vila Santandreu and Rosalía Valero San Cecilio and Verónica López Jiménez and Montserrat Carmona-Rodríguez and Luis A López-Fernández and Iñaki Imaz-Iglesia and María del Mar García-Saiz and Magí Farré and Consuelo Rodriguez-Jimenez and Judith Sanabria-Cabrera and Rocío Rosas-Alonso and Irene García-García and Alberto M Borobia},
  year = {2026},
  journal = {BMJ Open},
  doi = {10.1136/bmjopen-2025-109279},
  url = {https://doi.org/10.1136/bmjopen-2025-109279}
}

RIS

TY  - JOUR
TI  - Multicentre, controlled, randomised and single-blind, adaptive phase IV protocol to evaluate effectiveness and cost-effectiveness of a pre-emptive genotyping strategy to optimise tacrolimus dosage in a pretransplant chronic kidney disease population cohort: iPHARMGx TRANSPGx nested clinical trial
AU  - Enrique Seco-Meseguer
AU  - Stefan Stewart
AU  - Elena Diago-Sempere
AU  - Carlos Jiménez
AU  - Nicolas Macías Carmona
AU  - Juan Fernández Solís
AU  - Anna Vila Santandreu
AU  - Rosalía Valero San Cecilio
AU  - Verónica López Jiménez
AU  - Montserrat Carmona-Rodríguez
AU  - Luis A López-Fernández
AU  - Iñaki Imaz-Iglesia
AU  - María del Mar García-Saiz
AU  - Magí Farré
AU  - Consuelo Rodriguez-Jimenez
AU  - Judith Sanabria-Cabrera
AU  - Rocío Rosas-Alonso
AU  - Irene García-García
AU  - Alberto M Borobia
PY  - 2026
JO  - BMJ Open
DO  - 10.1136/bmjopen-2025-109279
UR  - https://doi.org/10.1136/bmjopen-2025-109279
ER  - 

APA

Seco-Meseguer, E., Stewart, S., Diago-Sempere, E., Jiménez, C., Carmona, N. M., Solís, J. F., Santandreu, A. V., Cecilio, R. V. S., Jiménez, V. L., Carmona-Rodríguez, M., López-Fernández, L. A., Imaz-Iglesia, I., García-Saiz, M. D. M., Farré, M., Rodriguez-Jimenez, C., Sanabria-Cabrera, J., Rosas-Alonso, R., García-García, I., & Borobia, A. M. (2026). Multicentre, controlled, randomised and single-blind, adaptive phase IV protocol to evaluate effectiveness and cost-effectiveness of a pre-emptive genotyping strategy to optimise tacrolimus dosage in a pretransplant chronic kidney disease population cohort: iPHARMGx TRANSPGx nested clinical trial. BMJ Open. https://doi.org/10.1136/bmjopen-2025-109279

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