Evaluation of the performance and safety of adding the iron chelator MEX-CD1 to dialysate during continuous veno-venous haemodialysis for removing excess labile iron in intensive care patients with sepsis-associated acute kidney injury - the Iron in Intensive Care trial (IRON-I.C.): protocol for a phase I-II randomised crossover pilot study.

Couturier A, Serrand C, Masseguin C, Allaouchiche B, Tillement O, Lefrant JY, Barbar SD

DOI: 10.1136/bmjopen-2025-109783
Published: 2025 Dec 23
Container: BMJ open
Publisher: Not recorded
Open access: yes

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Cite this work

BibTeX

@article{allodium:10.1136/bmjopen-2025-109783,
  title = {Evaluation of the performance and safety of adding the iron chelator MEX-CD1 to dialysate during continuous veno-venous haemodialysis for removing excess labile iron in intensive care patients with sepsis-associated acute kidney injury - the Iron in Intensive Care trial (IRON-I.C.): protocol for a phase I-II randomised crossover pilot study.},
  author = {Couturier A and Serrand C and Masseguin C and Allaouchiche B and Tillement O and Lefrant JY and Barbar SD},
  year = {2025},
  journal = {BMJ open},
  doi = {10.1136/bmjopen-2025-109783},
  url = {https://doi.org/10.1136/bmjopen-2025-109783}
}

RIS

TY  - JOUR
TI  - Evaluation of the performance and safety of adding the iron chelator MEX-CD1 to dialysate during continuous veno-venous haemodialysis for removing excess labile iron in intensive care patients with sepsis-associated acute kidney injury - the Iron in Intensive Care trial (IRON-I.C.): protocol for a phase I-II randomised crossover pilot study.
AU  - Couturier A
AU  - Serrand C
AU  - Masseguin C
AU  - Allaouchiche B
AU  - Tillement O
AU  - Lefrant JY
AU  - Barbar SD
PY  - 2025
JO  - BMJ open
DO  - 10.1136/bmjopen-2025-109783
UR  - https://doi.org/10.1136/bmjopen-2025-109783
ER  -

APA

A, C., C, S., C, M., B, A., O, T., JY, L., & SD, B. (2025). Evaluation of the performance and safety of adding the iron chelator MEX-CD1 to dialysate during continuous veno-venous haemodialysis for removing excess labile iron in intensive care patients with sepsis-associated acute kidney injury - the Iron in Intensive Care trial (IRON-I.C.): protocol for a phase I-II randomised crossover pilot study.. BMJ open. https://doi.org/10.1136/bmjopen-2025-109783

Source records

pubmed · retrieved 2026-11-10T12:59:37.015Z