MELODY trial: study protocol for a 12-week randomised controlled trial of adjunctive melatonin, digital cognitive behavioural therapy for insomnia or pill placebo to improve depressive symptoms in young adults with mood disorders.

Crouse JJ, Shin M, Hockey SJ, Jeon E, Bradshaw N, Nichles A, Zmicerevska N, Chong MK, You H, Wray NR, Scott J, Grunstein RR, Naismith SL, Merikangas KR, Cain SW, Medland SE, Iorfino F, Uebergang TD, McKenna S, Carpenter JS, Tonini E, Bhattacharya N, Hamilton BA, Wallace LM, Henders AK, Scott EM, Song YJC, Brain and Mind Centre Lived Experience Working Group, Hickie IB

Open source

DOI: 10.1136/bmjopen-2025-114817
Published: 2026 Aug 24
Container: BMJ open
Publisher: Not recorded
Open access: yes

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Cite this work

BibTeX

@article{allodium:10.1136/bmjopen-2025-114817,
  title = {MELODY trial: study protocol for a 12-week randomised controlled trial of adjunctive melatonin, digital cognitive behavioural therapy for insomnia or pill placebo to improve depressive symptoms in young adults with mood disorders.},
  author = {Crouse JJ and Shin M and Hockey SJ and Jeon E and Bradshaw N and Nichles A and Zmicerevska N and Chong MK and You H and Wray NR and Scott J and Grunstein RR and Naismith SL and Merikangas KR and Cain SW and Medland SE and Iorfino F and Uebergang TD and McKenna S and Carpenter JS and Tonini E and Bhattacharya N and Hamilton BA and Wallace LM and Henders AK and Scott EM and Song YJC and Brain and Mind Centre Lived Experience Working Group and Hickie IB},
  year = {2026},
  journal = {BMJ open},
  doi = {10.1136/bmjopen-2025-114817},
  url = {https://doi.org/10.1136/bmjopen-2025-114817}
}

RIS

TY  - JOUR
TI  - MELODY trial: study protocol for a 12-week randomised controlled trial of adjunctive melatonin, digital cognitive behavioural therapy for insomnia or pill placebo to improve depressive symptoms in young adults with mood disorders.
AU  - Crouse JJ
AU  - Shin M
AU  - Hockey SJ
AU  - Jeon E
AU  - Bradshaw N
AU  - Nichles A
AU  - Zmicerevska N
AU  - Chong MK
AU  - You H
AU  - Wray NR
AU  - Scott J
AU  - Grunstein RR
AU  - Naismith SL
AU  - Merikangas KR
AU  - Cain SW
AU  - Medland SE
AU  - Iorfino F
AU  - Uebergang TD
AU  - McKenna S
AU  - Carpenter JS
AU  - Tonini E
AU  - Bhattacharya N
AU  - Hamilton BA
AU  - Wallace LM
AU  - Henders AK
AU  - Scott EM
AU  - Song YJC
AU  - Brain and Mind Centre Lived Experience Working Group
AU  - Hickie IB
PY  - 2026
JO  - BMJ open
DO  - 10.1136/bmjopen-2025-114817
UR  - https://doi.org/10.1136/bmjopen-2025-114817
ER  -

APA

JJ, C., M, S., SJ, H., E, J., N, B., A, N., N, Z., MK, C., H, Y., NR, W., J, S., RR, G., SL, N., KR, M., SW, C., SE, M., F, I., TD, U., S, M., JS, C., E, T., N, B., BA, H., LM, W., AK, H., EM, S., YJC, S., Group, B. A. M. C. L. E. W., & IB, H. (2026). MELODY trial: study protocol for a 12-week randomised controlled trial of adjunctive melatonin, digital cognitive behavioural therapy for insomnia or pill placebo to improve depressive symptoms in young adults with mood disorders.. BMJ open. https://doi.org/10.1136/bmjopen-2025-114817

Source records

pubmed · retrieved 2026-09-25T17:28:01.720Z
europe-pmc · retrieved 2026-09-25T17:28:01.736Z
doaj · retrieved 2026-09-25T17:28:01.736Z