Clinical and cost-effectiveness of oral versus intramuscular glucocorticoids in rheumatoid arthritis: protocol for a multicentre randomised controlled trial with economic evaluation and qualitative sub-study (LEADER trial)

Jonathan Alistair Cook, Nicky Wilson, Kate Wilkins, Karen Staniland, Iniobong Ekang, Shazli Azmi, Liam Heaney, Sean P Gavan, Rachel Ann Elliott, Robert J Wilson, Clare Calvert, Anne Francis, Jennifer Anne Elizabeth Williams, Anabella Turner, Alex Zimmermann, Duncan Richards, Anne Barton, James Bluett

Open source

DOI: 10.1136/bmjopen-2026-119885
Published: 2026-07
Container: BMJ Open
Publisher: BMJ
Open access: unknown

Credibility signals

uncertain Score 64/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

supportingDOI registered: A matching record was returned by Crossref. Source: Crossref; license: CC0 metadata
supportingDOI resolves: A matching record was returned by Crossref. Source: Crossref; license: CC0 metadata
not scoredDirectory of Open Access Journals: No matching DOAJ record was present in this response. No allow-list match; this is not evidence of low credibility. Source: DOAJ; license: CC0
not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredROR affiliation: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredOpen access status: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication license: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication version: A publication version was supplied but is not scored. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
supportingMetadata completeness: All 6 scored descriptive metadata groups are present. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

Cite this work

BibTeX

@article{allodium:10.1136/bmjopen-2026-119885,
  title = {Clinical and cost-effectiveness of oral versus intramuscular glucocorticoids in rheumatoid arthritis: protocol for a multicentre randomised controlled trial with economic evaluation and qualitative sub-study (LEADER trial)},
  author = {Jonathan Alistair Cook and Nicky Wilson and Kate Wilkins and Karen Staniland and Iniobong Ekang and Shazli Azmi and Liam Heaney and Sean P Gavan and Rachel Ann Elliott and Robert J Wilson and Clare Calvert and Anne Francis and Jennifer Anne Elizabeth Williams and Anabella Turner and Alex Zimmermann and Duncan Richards and Anne Barton and James Bluett},
  year = {2026},
  journal = {BMJ Open},
  doi = {10.1136/bmjopen-2026-119885},
  url = {https://doi.org/10.1136/bmjopen-2026-119885}
}

RIS

TY  - JOUR
TI  - Clinical and cost-effectiveness of oral versus intramuscular glucocorticoids in rheumatoid arthritis: protocol for a multicentre randomised controlled trial with economic evaluation and qualitative sub-study (LEADER trial)
AU  - Jonathan Alistair Cook
AU  - Nicky Wilson
AU  - Kate Wilkins
AU  - Karen Staniland
AU  - Iniobong Ekang
AU  - Shazli Azmi
AU  - Liam Heaney
AU  - Sean P Gavan
AU  - Rachel Ann Elliott
AU  - Robert J Wilson
AU  - Clare Calvert
AU  - Anne Francis
AU  - Jennifer Anne Elizabeth Williams
AU  - Anabella Turner
AU  - Alex Zimmermann
AU  - Duncan Richards
AU  - Anne Barton
AU  - James Bluett
PY  - 2026
JO  - BMJ Open
DO  - 10.1136/bmjopen-2026-119885
UR  - https://doi.org/10.1136/bmjopen-2026-119885
ER  -

APA

Cook, J. A., Wilson, N., Wilkins, K., Staniland, K., Ekang, I., Azmi, S., Heaney, L., Gavan, S. P., Elliott, R. A., Wilson, R. J., Calvert, C., Francis, A., Williams, J. A. E., Turner, A., Zimmermann, A., Richards, D., Barton, A., & Bluett, J. (2026). Clinical and cost-effectiveness of oral versus intramuscular glucocorticoids in rheumatoid arthritis: protocol for a multicentre randomised controlled trial with economic evaluation and qualitative sub-study (LEADER trial). BMJ Open. https://doi.org/10.1136/bmjopen-2026-119885

Source records

crossref · retrieved 2026-09-27T08:41:32.868Z