Sleeping Beauty mutagenesis identifies BACH2 and other regulators of CD8(+) T-cell exhaustion, persistence in vivo, and CAR-T cell function under tumor-associated chronic antigen stimulation.

Lee CJ, Larsson AT, Jubenville TA, Hudson WA, Seeman ZJ, Stewart C, Tsai AK, Burrack A, Kimball BL, Siegler EL, Vianzon VV, Nolan EE, Yang YL, Stehn CM, Gohl DM, Donovan M, Temiz NA, Popescu FE, Warming S, Seshagiri S, You Y, Riordan JD, Dupuy A, Moriarity B, Rogers L, Stromnes I, Kenderian S, Largaespada D

Open source

DOI: 10.1136/jitc-2025-013536
Published: 2026 Jul 15
Container: Journal for immunotherapy of cancer
Publisher: Not recorded
Open access: yes

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Cite this work

BibTeX

@article{allodium:10.1136/jitc-2025-013536,
  title = {Sleeping Beauty mutagenesis identifies BACH2 and other regulators of CD8(+) T-cell exhaustion, persistence in vivo, and CAR-T cell function under tumor-associated chronic antigen stimulation.},
  author = {Lee CJ and Larsson AT and Jubenville TA and Hudson WA and Seeman ZJ and Stewart C and Tsai AK and Burrack A and Kimball BL and Siegler EL and Vianzon VV and Nolan EE and Yang YL and Stehn CM and Gohl DM and Donovan M and Temiz NA and Popescu FE and Warming S and Seshagiri S and You Y and Riordan JD and Dupuy A and Moriarity B and Rogers L and Stromnes I and Kenderian S and Largaespada D},
  year = {2026},
  journal = {Journal for immunotherapy of cancer},
  doi = {10.1136/jitc-2025-013536},
  url = {https://doi.org/10.1136/jitc-2025-013536}
}

RIS

TY  - JOUR
TI  - Sleeping Beauty mutagenesis identifies BACH2 and other regulators of CD8(+) T-cell exhaustion, persistence in vivo, and CAR-T cell function under tumor-associated chronic antigen stimulation.
AU  - Lee CJ
AU  - Larsson AT
AU  - Jubenville TA
AU  - Hudson WA
AU  - Seeman ZJ
AU  - Stewart C
AU  - Tsai AK
AU  - Burrack A
AU  - Kimball BL
AU  - Siegler EL
AU  - Vianzon VV
AU  - Nolan EE
AU  - Yang YL
AU  - Stehn CM
AU  - Gohl DM
AU  - Donovan M
AU  - Temiz NA
AU  - Popescu FE
AU  - Warming S
AU  - Seshagiri S
AU  - You Y
AU  - Riordan JD
AU  - Dupuy A
AU  - Moriarity B
AU  - Rogers L
AU  - Stromnes I
AU  - Kenderian S
AU  - Largaespada D
PY  - 2026
JO  - Journal for immunotherapy of cancer
DO  - 10.1136/jitc-2025-013536
UR  - https://doi.org/10.1136/jitc-2025-013536
ER  -

APA

CJ, L., AT, L., TA, J., WA, H., ZJ, S., C, S., AK, T., A, B., BL, K., EL, S., VV, V., EE, N., YL, Y., CM, S., DM, G., M, D., NA, T., FE, P., S, W., S, S., Y, Y., JD, R., A, D., B, M., L, R., I, S., S, K., & D, L. (2026). Sleeping Beauty mutagenesis identifies BACH2 and other regulators of CD8(+) T-cell exhaustion, persistence in vivo, and CAR-T cell function under tumor-associated chronic antigen stimulation.. Journal for immunotherapy of cancer. https://doi.org/10.1136/jitc-2025-013536

Source records

pubmed · retrieved 2026-09-25T10:44:38.559Z