Clinical development and proof of principle testing of new regenerative vascular endothelial growth factor-D therapy for refractory angina: rationale and design of the phase 2 ReGenHeart trial.

Leikas AJ, Hartikainen JEK, Kastrup J, Mathur A, Gyöngyösi M, Fernández-Avilés F, Sanz-Ruiz R, Wojakowski W, Gwizdała A, Luite R, Nikkinen M, Qayyum AA, Haack-Sørensen M, Kelham M, Jones DA, Hamzaraj K, Spannbauer A, Fernández-Santos ME, Jędrzejek M, Skoczyńska A, Vartiainen N, Knuuti J, Saraste A, Ylä-Herttuala S.

Open source

DOI: 10.1136/openhrt-2024-002817
Published: 2024-10-17
Container: Open Heart
Publisher: Not recorded
Open access: yes

Credibility signals

uncertain Score 53/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

cautionDOI registered: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
cautionDOI resolves: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
supportingDirectory of Open Access Journals: A matching record was returned by DOAJ. Source: DOAJ; license: CC0
not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredROR affiliation: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
supportingOpen access status: Normalized open-access status: open. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
not scoredPublication license: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication version: A publication version was supplied but is not scored. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
cautionMetadata completeness: 5 of 6 scored descriptive metadata groups are present; missing fields increase uncertainty. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

Cite this work

BibTeX

@article{allodium:10.1136/openhrt-2024-002817,
  title = {Clinical development and proof of principle testing of new regenerative vascular endothelial growth factor-D therapy for refractory angina: rationale and design of the phase 2 ReGenHeart trial.},
  author = {Leikas AJ and  Hartikainen JEK and  Kastrup J and  Mathur A and  Gyöngyösi M and  Fernández-Avilés F and  Sanz-Ruiz R and  Wojakowski W and  Gwizdała A and  Luite R and  Nikkinen M and  Qayyum AA and  Haack-Sørensen M and  Kelham M and  Jones DA and  Hamzaraj K and  Spannbauer A and  Fernández-Santos ME and  Jędrzejek M and  Skoczyńska A and  Vartiainen N and  Knuuti J and  Saraste A and  Ylä-Herttuala S.},
  year = {2024},
  journal = {Open Heart},
  doi = {10.1136/openhrt-2024-002817},
  url = {https://doi.org/10.1136/openhrt-2024-002817}
}

RIS

TY  - JOUR
TI  - Clinical development and proof of principle testing of new regenerative vascular endothelial growth factor-D therapy for refractory angina: rationale and design of the phase 2 ReGenHeart trial.
AU  - Leikas AJ
AU  -  Hartikainen JEK
AU  -  Kastrup J
AU  -  Mathur A
AU  -  Gyöngyösi M
AU  -  Fernández-Avilés F
AU  -  Sanz-Ruiz R
AU  -  Wojakowski W
AU  -  Gwizdała A
AU  -  Luite R
AU  -  Nikkinen M
AU  -  Qayyum AA
AU  -  Haack-Sørensen M
AU  -  Kelham M
AU  -  Jones DA
AU  -  Hamzaraj K
AU  -  Spannbauer A
AU  -  Fernández-Santos ME
AU  -  Jędrzejek M
AU  -  Skoczyńska A
AU  -  Vartiainen N
AU  -  Knuuti J
AU  -  Saraste A
AU  -  Ylä-Herttuala S.
PY  - 2024
JO  - Open Heart
DO  - 10.1136/openhrt-2024-002817
UR  - https://doi.org/10.1136/openhrt-2024-002817
ER  -

APA

AJ, L., JEK, H., J, K., A, M., M, G., F, F., R, S., W, W., A, G., R, L., M, N., AA, Q., M, H., M, K., DA, J., K, H., A, S., ME, F., M, J., A, S., N, V., J, K., A, S., & S., Y. (2024). Clinical development and proof of principle testing of new regenerative vascular endothelial growth factor-D therapy for refractory angina: rationale and design of the phase 2 ReGenHeart trial.. Open Heart. https://doi.org/10.1136/openhrt-2024-002817

Source records

europe-pmc · retrieved 2026-09-25T16:33:21.173Z
doaj · retrieved 2026-09-25T16:33:21.205Z