TNG917 is a Potent and Selective Inhibitor of Histone Lysine Methyltransferases EHMT1/2 that Enhances Antitumor Immunity and Immunotherapy Efficacy

Alvin Ziying Lu, Brian B. Haines, Wenhai Zhang, Minjie Zhang, Douglas A. Whittington, Lei Ji, Teng Teng, Maria Dam Ferdinez, Yi Yu, Hongxiang Zhang, Lina Gu, Alice W. Tsai, Sirimas Sudsakorn, William D. Mallender, Brett D. Williams, Jon H. Come, Scott Throner, Joseph P. Vacca, Alan Huang, Chengyin Min, John P. Maxwell, Jannik N. Andersen, Ying-Nan P. Chen

Open source

DOI: 10.1158/0008-5472.can-25-4720
Published: 2026-06-10
Container: Cancer Research
Publisher: American Association for Cancer Research (AACR)
Open access: unknown

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Cite this work

BibTeX

@article{allodium:10.1158/0008-5472.can-25-4720,
  title = {TNG917 is a Potent and Selective Inhibitor of Histone Lysine Methyltransferases EHMT1/2 that Enhances Antitumor Immunity and Immunotherapy Efficacy},
  author = {Alvin Ziying Lu and Brian B. Haines and Wenhai Zhang and Minjie Zhang and Douglas A. Whittington and Lei Ji and Teng Teng and Maria Dam Ferdinez and Yi Yu and Hongxiang Zhang and Lina Gu and Alice W. Tsai and Sirimas Sudsakorn and William D. Mallender and Brett D. Williams and Jon H. Come and Scott Throner and Joseph P. Vacca and Alan Huang and Chengyin Min and John P. Maxwell and Jannik N. Andersen and Ying-Nan P. Chen},
  year = {2026},
  journal = {Cancer Research},
  doi = {10.1158/0008-5472.can-25-4720},
  url = {https://doi.org/10.1158/0008-5472.can-25-4720}
}

RIS

TY  - JOUR
TI  - TNG917 is a Potent and Selective Inhibitor of Histone Lysine Methyltransferases EHMT1/2 that Enhances Antitumor Immunity and Immunotherapy Efficacy
AU  - Alvin Ziying Lu
AU  - Brian B. Haines
AU  - Wenhai Zhang
AU  - Minjie Zhang
AU  - Douglas A. Whittington
AU  - Lei Ji
AU  - Teng Teng
AU  - Maria Dam Ferdinez
AU  - Yi Yu
AU  - Hongxiang Zhang
AU  - Lina Gu
AU  - Alice W. Tsai
AU  - Sirimas Sudsakorn
AU  - William D. Mallender
AU  - Brett D. Williams
AU  - Jon H. Come
AU  - Scott Throner
AU  - Joseph P. Vacca
AU  - Alan Huang
AU  - Chengyin Min
AU  - John P. Maxwell
AU  - Jannik N. Andersen
AU  - Ying-Nan P. Chen
PY  - 2026
JO  - Cancer Research
DO  - 10.1158/0008-5472.can-25-4720
UR  - https://doi.org/10.1158/0008-5472.can-25-4720
ER  -

APA

Lu, A. Z., Haines, B. B., Zhang, W., Zhang, M., Whittington, D. A., Ji, L., Teng, T., Ferdinez, M. D., Yu, Y., Zhang, H., Gu, L., Tsai, A. W., Sudsakorn, S., Mallender, W. D., Williams, B. D., Come, J. H., Throner, S., Vacca, J. P., Huang, A., Min, C., Maxwell, J. P., Andersen, J. N., & Chen, Y. P. (2026). TNG917 is a Potent and Selective Inhibitor of Histone Lysine Methyltransferases EHMT1/2 that Enhances Antitumor Immunity and Immunotherapy Efficacy. Cancer Research. https://doi.org/10.1158/0008-5472.can-25-4720

Source records

crossref · retrieved 2026-09-26T00:46:46.249Z