A Phase I, First-in-Human, Dose-Escalation, Expansion Trial of Cytokine-Encoding Synthetic mRNA Mixture Alone or with Cemiplimab in Advanced Solid Tumors

Oliver Bechter, Carmen Loquai, Stephane Champiat, Jean-Francois Baurain, Jean-Jacques Grob, Jochen Utikal, Sylvie Rottey, Alfonso Berrocal, Jessica C. Hassel, Ana Arance, Miguel F. Sanmamed, Marye Boers-Sonderen, Brian Gastman, Christoffer Gebhardt, Brant Delafontaine, Ugur Sahin, Özlem Türeci, Patrick Brueck, Giovanni Abbadessa, Rahul Marpadga, Helen Lee, Yue Yang, Barbara Buday, Gianfranco Di Genova, Hong Wang, Binfeng Xia, Joon Sang Lee, Céleste Lebbe

Open source

DOI: 10.1158/1078-0432.ccr-24-1983
Published: 2025-03-28
Container: Clinical Cancer Research
Publisher: American Association for Cancer Research (AACR)
Open access: unknown

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Cite this work

BibTeX

@article{allodium:10.1158/1078-0432.ccr-24-1983,
  title = {A Phase I, First-in-Human, Dose-Escalation, Expansion Trial of Cytokine-Encoding Synthetic mRNA Mixture Alone or with Cemiplimab in Advanced Solid Tumors},
  author = {Oliver Bechter and Carmen Loquai and Stephane Champiat and Jean-Francois Baurain and Jean-Jacques Grob and Jochen Utikal and Sylvie Rottey and Alfonso Berrocal and Jessica C. Hassel and Ana Arance and Miguel F. Sanmamed and Marye Boers-Sonderen and Brian Gastman and Christoffer Gebhardt and Brant Delafontaine and Ugur Sahin and Özlem Türeci and Patrick Brueck and Giovanni Abbadessa and Rahul Marpadga and Helen Lee and Yue Yang and Barbara Buday and Gianfranco Di Genova and Hong Wang and Binfeng Xia and Joon Sang Lee and Céleste Lebbe},
  year = {2025},
  journal = {Clinical Cancer Research},
  doi = {10.1158/1078-0432.ccr-24-1983},
  url = {https://doi.org/10.1158/1078-0432.ccr-24-1983}
}

RIS

TY  - JOUR
TI  - A Phase I, First-in-Human, Dose-Escalation, Expansion Trial of Cytokine-Encoding Synthetic mRNA Mixture Alone or with Cemiplimab in Advanced Solid Tumors
AU  - Oliver Bechter
AU  - Carmen Loquai
AU  - Stephane Champiat
AU  - Jean-Francois Baurain
AU  - Jean-Jacques Grob
AU  - Jochen Utikal
AU  - Sylvie Rottey
AU  - Alfonso Berrocal
AU  - Jessica C. Hassel
AU  - Ana Arance
AU  - Miguel F. Sanmamed
AU  - Marye Boers-Sonderen
AU  - Brian Gastman
AU  - Christoffer Gebhardt
AU  - Brant Delafontaine
AU  - Ugur Sahin
AU  - Özlem Türeci
AU  - Patrick Brueck
AU  - Giovanni Abbadessa
AU  - Rahul Marpadga
AU  - Helen Lee
AU  - Yue Yang
AU  - Barbara Buday
AU  - Gianfranco Di Genova
AU  - Hong Wang
AU  - Binfeng Xia
AU  - Joon Sang Lee
AU  - Céleste Lebbe
PY  - 2025
JO  - Clinical Cancer Research
DO  - 10.1158/1078-0432.ccr-24-1983
UR  - https://doi.org/10.1158/1078-0432.ccr-24-1983
ER  -

APA

Bechter, O., Loquai, C., Champiat, S., Baurain, J., Grob, J., Utikal, J., Rottey, S., Berrocal, A., Hassel, J. C., Arance, A., Sanmamed, M. F., Boers-Sonderen, M., Gastman, B., Gebhardt, C., Delafontaine, B., Sahin, U., Türeci, Ö., Brueck, P., Abbadessa, G., Marpadga, R., Lee, H., Yang, Y., Buday, B., Genova, G. D., Wang, H., Xia, B., Lee, J. S., & Lebbe, C. (2025). A Phase I, First-in-Human, Dose-Escalation, Expansion Trial of Cytokine-Encoding Synthetic mRNA Mixture Alone or with Cemiplimab in Advanced Solid Tumors. Clinical Cancer Research. https://doi.org/10.1158/1078-0432.ccr-24-1983

Source records

crossref · retrieved 2026-09-26T08:23:33.441Z