Impact of Co-mutations and Transcriptional Signatures in Non–Small Cell Lung Cancer Patients Treated with Adagrasib in the KRYSTAL-1 Trial

Marcelo V. Negrao, Alvaro G. Paula, David Molkentine, Laura Hover, Monique Nilsson, Natalie Vokes, Lars Engstrom, Andrew Calinisan, David M. Briere, Laura Waters, Jill Hallin, Lixia Diao, Mehmet Altan, George R. Blumenschein, Ferdinandos Skoulidis, Jing Wang, Scott E. Kopetz, David S. Hong, Don L. Gibbons, Peter Olson, James G. Christensen, John V. Heymach

Open source

DOI: 10.1158/1078-0432.ccr-24-2310
Published: 2025-01-13
Container: Clinical Cancer Research
Publisher: American Association for Cancer Research (AACR)
Open access: unknown

Credibility signals

uncertain Score 64/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

supportingDOI registered: A matching record was returned by Crossref. Source: Crossref; license: CC0 metadata
supportingDOI resolves: A matching record was returned by Crossref. Source: Crossref; license: CC0 metadata
not scoredDirectory of Open Access Journals: No matching DOAJ record was present in this response. No allow-list match; this is not evidence of low credibility. Source: DOAJ; license: CC0
not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredROR affiliation: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredOpen access status: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication license: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication version: A publication version was supplied but is not scored. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
supportingMetadata completeness: All 6 scored descriptive metadata groups are present. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

Cite this work

BibTeX

@article{allodium:10.1158/1078-0432.ccr-24-2310,
  title = {Impact of Co-mutations and Transcriptional Signatures in Non–Small Cell Lung Cancer Patients Treated with Adagrasib in the KRYSTAL-1 Trial},
  author = {Marcelo V. Negrao and Alvaro G. Paula and David Molkentine and Laura Hover and Monique Nilsson and Natalie Vokes and Lars Engstrom and Andrew Calinisan and David M. Briere and Laura Waters and Jill Hallin and Lixia Diao and Mehmet Altan and George R. Blumenschein and Ferdinandos Skoulidis and Jing Wang and Scott E. Kopetz and David S. Hong and Don L. Gibbons and Peter Olson and James G. Christensen and John V. Heymach},
  year = {2025},
  journal = {Clinical Cancer Research},
  doi = {10.1158/1078-0432.ccr-24-2310},
  url = {https://doi.org/10.1158/1078-0432.ccr-24-2310}
}

RIS

TY  - JOUR
TI  - Impact of Co-mutations and Transcriptional Signatures in Non–Small Cell Lung Cancer Patients Treated with Adagrasib in the KRYSTAL-1 Trial
AU  - Marcelo V. Negrao
AU  - Alvaro G. Paula
AU  - David Molkentine
AU  - Laura Hover
AU  - Monique Nilsson
AU  - Natalie Vokes
AU  - Lars Engstrom
AU  - Andrew Calinisan
AU  - David M. Briere
AU  - Laura Waters
AU  - Jill Hallin
AU  - Lixia Diao
AU  - Mehmet Altan
AU  - George R. Blumenschein
AU  - Ferdinandos Skoulidis
AU  - Jing Wang
AU  - Scott E. Kopetz
AU  - David S. Hong
AU  - Don L. Gibbons
AU  - Peter Olson
AU  - James G. Christensen
AU  - John V. Heymach
PY  - 2025
JO  - Clinical Cancer Research
DO  - 10.1158/1078-0432.ccr-24-2310
UR  - https://doi.org/10.1158/1078-0432.ccr-24-2310
ER  -

APA

Negrao, M. V., Paula, A. G., Molkentine, D., Hover, L., Nilsson, M., Vokes, N., Engstrom, L., Calinisan, A., Briere, D. M., Waters, L., Hallin, J., Diao, L., Altan, M., Blumenschein, G. R., Skoulidis, F., Wang, J., Kopetz, S. E., Hong, D. S., Gibbons, D. L., Olson, P., Christensen, J. G., & Heymach, J. V. (2025). Impact of Co-mutations and Transcriptional Signatures in Non–Small Cell Lung Cancer Patients Treated with Adagrasib in the KRYSTAL-1 Trial. Clinical Cancer Research. https://doi.org/10.1158/1078-0432.ccr-24-2310

Source records

crossref · retrieved 2026-09-26T14:15:46.240Z