plasmaCHORD: A Machine Learning Approach to Distinguish Clonal Hematopoiesis–Derived Variants in Liquid Biopsies from Patients with Solid Tumors

Jenna V. Canzoniero, Daniel Rabizadeh, Ilias Ziakas, Jaime Wehr, Archana Balan, Amna Jamali, Blair V. Landon, Lavanya Sivapalan, Susan Scott, Gavin Pereira, Vincent K. Lam, Christine L. Hann, Christine M. Lovly, Jessica Tao, Patrick M. Forde, Joseph C. Murray, Mark Sausen, Gerrit A. Meijer, Geraldine R. Vink, Remond J.A. Fijneman, Unknown, E.J.T. Belt, M.A. Davidis, I.H.J.T. de Hingh, A.I. de Vos, J.W.T. Dekker, A.W. Haringhuizen, M.P. Hendriks, R. Hoekstra, J. Jansen, J.J.B. Janssen, F.J.F. Jeurissen, F.W.H. Kloppenberg, J.L.M. Konsten, Miriam Koopman, Maartje Los, P. Nieboer, N.A.J.B. Peters, J.F.M. Pruijt, R.C. Rietbroek, A.H.W. Schiphorst, R.W.M. Schrauwen, Jos Schreinemakers, L.H.J. Simkens, Dirkje W. Sommeijer, Hein B.A.C. Stockmann, Koen Talsma, Frederiek Terheggen, Manuel Tjin-A-Ton, L.B.J. Valkenburg, H. van Cruijsen, Jarmila van der Bilt, A.P. Schouten van der Velden, Joyce M. van Dodewaard, Teo van Voorthuizen, Wouter Vles, David Daniel Eisinga Zimmerman, Victor E. Velculescu, Jillian Phallen, Robert B. Scharpf, Valsamo Anagnostou

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DOI: 10.1158/1078-0432.ccr-25-0976
Published: 2026-04-19
Container: Clinical Cancer Research
Publisher: American Association for Cancer Research (AACR)
Open access: unknown

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Cite this work

BibTeX

@article{allodium:10.1158/1078-0432.ccr-25-0976,
title = {plasmaCHORD: A Machine Learning Approach to Distinguish Clonal Hematopoiesis–Derived Variants in Liquid Biopsies from Patients with Solid Tumors},
author = {Jenna V. Canzoniero and Daniel Rabizadeh and Ilias Ziakas and Jaime Wehr and Archana Balan and Amna Jamali and Blair V. Landon and Lavanya Sivapalan and Susan Scott and Gavin Pereira and Vincent K. Lam and Christine L. Hann and Christine M. Lovly and Jessica Tao and Patrick M. Forde and Joseph C. Murray and Mark Sausen and Gerrit A. Meijer and Geraldine R. Vink and Remond J.A. Fijneman and Unknown and E.J.T. Belt and M.A. Davidis and I.H.J.T. de Hingh and A.I. de Vos and J.W.T. Dekker and A.W. Haringhuizen and M.P. Hendriks and R. Hoekstra and J. Jansen and J.J.B. Janssen and F.J.F. Jeurissen and F.W.H. Kloppenberg and J.L.M. Konsten and Miriam Koopman and Maartje Los and P. Nieboer and N.A.J.B. Peters and J.F.M. Pruijt and R.C. Rietbroek and A.H.W. Schiphorst and R.W.M. Schrauwen and Jos Schreinemakers and L.H.J. Simkens and Dirkje W. Sommeijer and Hein B.A.C. Stockmann and Koen Talsma and Frederiek Terheggen and Manuel Tjin-A-Ton and L.B.J. Valkenburg and H. van Cruijsen and Jarmila van der Bilt and A.P. Schouten van der Velden and Joyce M. van Dodewaard and Teo van Voorthuizen and Wouter Vles and David Daniel Eisinga Zimmerman and Victor E. Velculescu and Jillian Phallen and Robert B. Scharpf and Valsamo Anagnostou},
year = {2026},
journal = {Clinical Cancer Research},
doi = {10.1158/1078-0432.ccr-25-0976},
url = {https://doi.org/10.1158/1078-0432.ccr-25-0976}
}

RIS

TY  - JOUR
TI  - plasmaCHORD: A Machine Learning Approach to Distinguish Clonal Hematopoiesis–Derived Variants in Liquid Biopsies from Patients with Solid Tumors
AU  - Jenna V. Canzoniero
AU  - Daniel Rabizadeh
AU  - Ilias Ziakas
AU  - Jaime Wehr
AU  - Archana Balan
AU  - Amna Jamali
AU  - Blair V. Landon
AU  - Lavanya Sivapalan
AU  - Susan Scott
AU  - Gavin Pereira
AU  - Vincent K. Lam
AU  - Christine L. Hann
AU  - Christine M. Lovly
AU  - Jessica Tao
AU  - Patrick M. Forde
AU  - Joseph C. Murray
AU  - Mark Sausen
AU  - Gerrit A. Meijer
AU  - Geraldine R. Vink
AU  - Remond J.A. Fijneman
AU  - Unknown
AU  - E.J.T. Belt
AU  - M.A. Davidis
AU  - I.H.J.T. de Hingh
AU  - A.I. de Vos
AU  - J.W.T. Dekker
AU  - A.W. Haringhuizen
AU  - M.P. Hendriks
AU  - R. Hoekstra
AU  - J. Jansen
AU  - J.J.B. Janssen
AU  - F.J.F. Jeurissen
AU  - F.W.H. Kloppenberg
AU  - J.L.M. Konsten
AU  - Miriam Koopman
AU  - Maartje Los
AU  - P. Nieboer
AU  - N.A.J.B. Peters
AU  - J.F.M. Pruijt
AU  - R.C. Rietbroek
AU  - A.H.W. Schiphorst
AU  - R.W.M. Schrauwen
AU  - Jos Schreinemakers
AU  - L.H.J. Simkens
AU  - Dirkje W. Sommeijer
AU  - Hein B.A.C. Stockmann
AU  - Koen Talsma
AU  - Frederiek Terheggen
AU  - Manuel Tjin-A-Ton
AU  - L.B.J. Valkenburg
AU  - H. van Cruijsen
AU  - Jarmila van der Bilt
AU  - A.P. Schouten van der Velden
AU  - Joyce M. van Dodewaard
AU  - Teo van Voorthuizen
AU  - Wouter Vles
AU  - David Daniel Eisinga Zimmerman
AU  - Victor E. Velculescu
AU  - Jillian Phallen
AU  - Robert B. Scharpf
AU  - Valsamo Anagnostou
PY  - 2026
JO  - Clinical Cancer Research
DO  - 10.1158/1078-0432.ccr-25-0976
UR  - https://doi.org/10.1158/1078-0432.ccr-25-0976
ER  -

APA

Canzoniero, J. V., Rabizadeh, D., Ziakas, I., Wehr, J., Balan, A., Jamali, A., Landon, B. V., Sivapalan, L., Scott, S., Pereira, G., Lam, V. K., Hann, C. L., Lovly, C. M., Tao, J., Forde, P. M., Murray, J. C., Sausen, M., Meijer, G. A., Vink, G. R., Fijneman, R. J., Unknown, Belt, E., Davidis, M., Hingh, I. D., Vos, A. D., Dekker, J., Haringhuizen, A., Hendriks, M., Hoekstra, R., Jansen, J., Janssen, J., Jeurissen, F., Kloppenberg, F., Konsten, J., Koopman, M., Los, M., Nieboer, P., Peters, N., Pruijt, J., Rietbroek, R., Schiphorst, A., Schrauwen, R., Schreinemakers, J., Simkens, L., Sommeijer, D. W., Stockmann, H. B., Talsma, K., Terheggen, F., Tjin-A-Ton, M., Valkenburg, L., Cruijsen, H. V., Bilt, J. V. D., Velden, A. S. V. D., Dodewaard, J. M. V., Voorthuizen, T. V., Vles, W., Zimmerman, D. D. E., Velculescu, V. E., Phallen, J., Scharpf, R. B., & Anagnostou, V. (2026). plasmaCHORD: A Machine Learning Approach to Distinguish Clonal Hematopoiesis–Derived Variants in Liquid Biopsies from Patients with Solid Tumors. Clinical Cancer Research. https://doi.org/10.1158/1078-0432.ccr-25-0976

Source records

crossref · retrieved 2026-09-26T04:51:45.090Z