Combinatorial Delivery of Low-Dose Radiotherapy and Immunotherapy to Patients with Immune-Excluded Tumors Enhances CD8+ T-cell Functionality

Maria Ochoa-de-Olza, Nicolas Rayroux, Martina Imbimbo, Angela Orcurto, Noémie Fahr, Fabrizio Benedetti, Julien Dagher, Giulia Spagnol, David Barras, Eleonora Ghisoni, Blanca Navarro, Arthur Mulvey, Dominik Berthold, Apostolos Sarivalasis, Khalil Zaman, Athina Stravodimou, Antonia Digklia, Rafael Duran, Clarisse Dromain, John O. Prior, Niklaus Schaefer, Stefan Zimmermann, Michel Obeid, Nikos Chalkidis, Tsourti Zoi, Bettina Bisig, Lionel Trueb, Doga C. Gulhan, Christine Sempoux, Urania Dafni, Stephanie Tissot, George Coukos, Fernanda G. Herrera, Denarda Dangaj Laniti

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DOI: 10.1158/1078-0432.ccr-25-2743
Published: 2026-04-17
Container: Clinical Cancer Research
Publisher: American Association for Cancer Research (AACR)
Open access: unknown

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Cite this work

BibTeX

@article{allodium:10.1158/1078-0432.ccr-25-2743,
  title = {Combinatorial Delivery of Low-Dose Radiotherapy and Immunotherapy to Patients with Immune-Excluded Tumors Enhances CD8+ T-cell Functionality},
  author = {Maria Ochoa-de-Olza and Nicolas Rayroux and Martina Imbimbo and Angela Orcurto and Noémie Fahr and Fabrizio Benedetti and Julien Dagher and Giulia Spagnol and David Barras and Eleonora Ghisoni and Blanca Navarro and Arthur Mulvey and Dominik Berthold and Apostolos Sarivalasis and Khalil Zaman and Athina Stravodimou and Antonia Digklia and Rafael Duran and Clarisse Dromain and John O. Prior and Niklaus Schaefer and Stefan Zimmermann and Michel Obeid and Nikos Chalkidis and Tsourti Zoi and Bettina Bisig and Lionel Trueb and Doga C. Gulhan and Christine Sempoux and Urania Dafni and Stephanie Tissot and George Coukos and Fernanda G. Herrera and Denarda Dangaj Laniti},
  year = {2026},
  journal = {Clinical Cancer Research},
  doi = {10.1158/1078-0432.ccr-25-2743},
  url = {https://doi.org/10.1158/1078-0432.ccr-25-2743}
}

RIS

TY  - JOUR
TI  - Combinatorial Delivery of Low-Dose Radiotherapy and Immunotherapy to Patients with Immune-Excluded Tumors Enhances CD8+ T-cell Functionality
AU  - Maria Ochoa-de-Olza
AU  - Nicolas Rayroux
AU  - Martina Imbimbo
AU  - Angela Orcurto
AU  - Noémie Fahr
AU  - Fabrizio Benedetti
AU  - Julien Dagher
AU  - Giulia Spagnol
AU  - David Barras
AU  - Eleonora Ghisoni
AU  - Blanca Navarro
AU  - Arthur Mulvey
AU  - Dominik Berthold
AU  - Apostolos Sarivalasis
AU  - Khalil Zaman
AU  - Athina Stravodimou
AU  - Antonia Digklia
AU  - Rafael Duran
AU  - Clarisse Dromain
AU  - John O. Prior
AU  - Niklaus Schaefer
AU  - Stefan Zimmermann
AU  - Michel Obeid
AU  - Nikos Chalkidis
AU  - Tsourti Zoi
AU  - Bettina Bisig
AU  - Lionel Trueb
AU  - Doga C. Gulhan
AU  - Christine Sempoux
AU  - Urania Dafni
AU  - Stephanie Tissot
AU  - George Coukos
AU  - Fernanda G. Herrera
AU  - Denarda Dangaj Laniti
PY  - 2026
JO  - Clinical Cancer Research
DO  - 10.1158/1078-0432.ccr-25-2743
UR  - https://doi.org/10.1158/1078-0432.ccr-25-2743
ER  -

APA

Ochoa-de-Olza, M., Rayroux, N., Imbimbo, M., Orcurto, A., Fahr, N., Benedetti, F., Dagher, J., Spagnol, G., Barras, D., Ghisoni, E., Navarro, B., Mulvey, A., Berthold, D., Sarivalasis, A., Zaman, K., Stravodimou, A., Digklia, A., Duran, R., Dromain, C., Prior, J. O., Schaefer, N., Zimmermann, S., Obeid, M., Chalkidis, N., Zoi, T., Bisig, B., Trueb, L., Gulhan, D. C., Sempoux, C., Dafni, U., Tissot, S., Coukos, G., Herrera, F. G., & Laniti, D. D. (2026). Combinatorial Delivery of Low-Dose Radiotherapy and Immunotherapy to Patients with Immune-Excluded Tumors Enhances CD8+ T-cell Functionality. Clinical Cancer Research. https://doi.org/10.1158/1078-0432.ccr-25-2743

Source records

crossref · retrieved 2026-09-26T13:03:45.420Z