The pharmacological profile of ART6043, a first-in-class clinical DNA polymerase theta polymerase domain inhibitor potentiating PARP inhibitor efficacy.

Robinson HMR, Grinkevich V, Majithiya JB, Mann SE, McWhirter C, Rajendra E, Ranzani M, Stockley ML, Costales P, Davis OA, Elinati E, Galbiati A, Geo L, Toste Rêgo A, Mason B, Armstrong L, Grande D, Neves J, Roy Luzarraga M, Cooper H, Edwardes L, Konstantinou T, van de Ven M, Moises da Silva A, Moser SC, Charles MD, Finch H, Higgins GS, Boulton SJ, Jonkers J, Martin NMB, Heald RA, Smith GCM

Open source

DOI: 10.1158/1078-0432.ccr-26-0493
Published: 2026 Jul 13
Container: Clinical cancer research : an official journal of the American Association for Cancer Research
Publisher: Not recorded
Open access: unknown

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Cite this work

BibTeX

@article{allodium:10.1158/1078-0432.ccr-26-0493,
  title = {The pharmacological profile of ART6043, a first-in-class clinical DNA polymerase theta polymerase domain inhibitor potentiating PARP inhibitor efficacy.},
  author = {Robinson HMR and Grinkevich V and Majithiya JB and Mann SE and McWhirter C and Rajendra E and Ranzani M and Stockley ML and Costales P and Davis OA and Elinati E and Galbiati A and Geo L and Toste Rêgo A and Mason B and Armstrong L and Grande D and Neves J and Roy Luzarraga M and Cooper H and Edwardes L and Konstantinou T and van de Ven M and Moises da Silva A and Moser SC and Charles MD and Finch H and Higgins GS and Boulton SJ and Jonkers J and Martin NMB and Heald RA and Smith GCM},
  year = {2026},
  journal = {Clinical cancer research : an official journal of the American Association for Cancer Research},
  doi = {10.1158/1078-0432.ccr-26-0493},
  url = {https://doi.org/10.1158/1078-0432.ccr-26-0493}
}

RIS

TY  - JOUR
TI  - The pharmacological profile of ART6043, a first-in-class clinical DNA polymerase theta polymerase domain inhibitor potentiating PARP inhibitor efficacy.
AU  - Robinson HMR
AU  - Grinkevich V
AU  - Majithiya JB
AU  - Mann SE
AU  - McWhirter C
AU  - Rajendra E
AU  - Ranzani M
AU  - Stockley ML
AU  - Costales P
AU  - Davis OA
AU  - Elinati E
AU  - Galbiati A
AU  - Geo L
AU  - Toste Rêgo A
AU  - Mason B
AU  - Armstrong L
AU  - Grande D
AU  - Neves J
AU  - Roy Luzarraga M
AU  - Cooper H
AU  - Edwardes L
AU  - Konstantinou T
AU  - van de Ven M
AU  - Moises da Silva A
AU  - Moser SC
AU  - Charles MD
AU  - Finch H
AU  - Higgins GS
AU  - Boulton SJ
AU  - Jonkers J
AU  - Martin NMB
AU  - Heald RA
AU  - Smith GCM
PY  - 2026
JO  - Clinical cancer research : an official journal of the American Association for Cancer Research
DO  - 10.1158/1078-0432.ccr-26-0493
UR  - https://doi.org/10.1158/1078-0432.ccr-26-0493
ER  -

APA

HMR, R., V, G., JB, M., SE, M., C, M., E, R., M, R., ML, S., P, C., OA, D., E, E., A, G., L, G., A, T. R., B, M., L, A., D, G., J, N., M, R. L., H, C., L, E., T, K., M, V. D. V., A, M. D. S., SC, M., MD, C., H, F., GS, H., SJ, B., J, J., NMB, M., RA, H., & GCM, S. (2026). The pharmacological profile of ART6043, a first-in-class clinical DNA polymerase theta polymerase domain inhibitor potentiating PARP inhibitor efficacy.. Clinical cancer research : an official journal of the American Association for Cancer Research. https://doi.org/10.1158/1078-0432.ccr-26-0493

Source records

pubmed · retrieved 2026-09-27T15:14:11.733Z