LIG1 Loss in TP53-mutant Triple Negative Breast Cancer Rewires DNA Repair and Confers Sensitivity to PARP-ATR Inhibitor Combinations.

Tran Huynh AM, Lei JT, Brough R, Sallas C, Xu J, Pilcher JB, Gou X, Wang J, Dobrolecki LE, Fandino DM, Berner MJ, Greer A, Song FF, Latka S, Villanueva H, Arimura S, Mao S, Guo Z, Aramburu SI, Chen A, Nguyen T, Gutierrez C, Lopez-Terrada DH, Lim B, Hilsenbeck SG, Lewis MT, Miles G, Mills JC, Echeverria GV, Pettitt SJ, Powell SN, Rosenberg SM, Tutt ANJ, Lord CJ, Ellis MJ, Anurag M

Open source

DOI: 10.1158/1535-7163.mct-26-0182
Published: 2026 Jul 15
Container: Molecular cancer therapeutics
Publisher: Not recorded
Open access: yes

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Cite this work

BibTeX

@article{allodium:10.1158/1535-7163.mct-26-0182,
  title = {LIG1 Loss in TP53-mutant Triple Negative Breast Cancer Rewires DNA Repair and Confers Sensitivity to PARP-ATR Inhibitor Combinations.},
  author = {Tran Huynh AM and Lei JT and Brough R and Sallas C and Xu J and Pilcher JB and Gou X and Wang J and Dobrolecki LE and Fandino DM and Berner MJ and Greer A and Song FF and Latka S and Villanueva H and Arimura S and Mao S and Guo Z and Aramburu SI and Chen A and Nguyen T and Gutierrez C and Lopez-Terrada DH and Lim B and Hilsenbeck SG and Lewis MT and Miles G and Mills JC and Echeverria GV and Pettitt SJ and Powell SN and Rosenberg SM and Tutt ANJ and Lord CJ and Ellis MJ and Anurag M},
  year = {2026},
  journal = {Molecular cancer therapeutics},
  doi = {10.1158/1535-7163.mct-26-0182},
  url = {https://doi.org/10.1158/1535-7163.mct-26-0182}
}

RIS

TY  - JOUR
TI  - LIG1 Loss in TP53-mutant Triple Negative Breast Cancer Rewires DNA Repair and Confers Sensitivity to PARP-ATR Inhibitor Combinations.
AU  - Tran Huynh AM
AU  - Lei JT
AU  - Brough R
AU  - Sallas C
AU  - Xu J
AU  - Pilcher JB
AU  - Gou X
AU  - Wang J
AU  - Dobrolecki LE
AU  - Fandino DM
AU  - Berner MJ
AU  - Greer A
AU  - Song FF
AU  - Latka S
AU  - Villanueva H
AU  - Arimura S
AU  - Mao S
AU  - Guo Z
AU  - Aramburu SI
AU  - Chen A
AU  - Nguyen T
AU  - Gutierrez C
AU  - Lopez-Terrada DH
AU  - Lim B
AU  - Hilsenbeck SG
AU  - Lewis MT
AU  - Miles G
AU  - Mills JC
AU  - Echeverria GV
AU  - Pettitt SJ
AU  - Powell SN
AU  - Rosenberg SM
AU  - Tutt ANJ
AU  - Lord CJ
AU  - Ellis MJ
AU  - Anurag M
PY  - 2026
JO  - Molecular cancer therapeutics
DO  - 10.1158/1535-7163.mct-26-0182
UR  - https://doi.org/10.1158/1535-7163.mct-26-0182
ER  -

APA

AM, T. H., JT, L., R, B., C, S., J, X., JB, P., X, G., J, W., LE, D., DM, F., MJ, B., A, G., FF, S., S, L., H, V., S, A., S, M., Z, G., SI, A., A, C., T, N., C, G., DH, L., B, L., SG, H., MT, L., G, M., JC, M., GV, E., SJ, P., SN, P., SM, R., ANJ, T., CJ, L., MJ, E., & M, A. (2026). LIG1 Loss in TP53-mutant Triple Negative Breast Cancer Rewires DNA Repair and Confers Sensitivity to PARP-ATR Inhibitor Combinations.. Molecular cancer therapeutics. https://doi.org/10.1158/1535-7163.mct-26-0182

Source records

pubmed · retrieved 2026-09-27T07:08:47.977Z