Blockade of Tumor-Intrinsic TGFβ Signaling Drives Hyperprogression in Small Cell Lung Cancer.

Schroeder BA, Mohindroo C, Meinhardt AL, Takahashi N, Zhang Y, Lee MJ, Sahoo S, Donahue RN, Kumar R, Nirula M, Yang Y, Rastogi S, Sato N, Lee S, Tsai YT, Zhuang S, Kazi A, Huang Y, Desai P, Nichols S, Sciuto L, Pinkiert D, Chrisafis G, Greenberg M, Biery DN, Al-Marayaty R, Yang HH, Lee MP, Schultz CW, El Meskini R, Atkinson D, Fousek K, Gulley JL, Schlom J, Sato M, Shrestha RL, Sharma AK, Jolly MK, Palena C, Wakefield LM, Thomas A

Open source

DOI: 10.1158/2159-8290.cd-25-1454
Published: 2026 Aug 3
Container: Cancer discovery
Publisher: Not recorded
Open access: yes

Credibility signals

limited evidence Score 45/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

cautionDOI registered: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
cautionDOI resolves: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
not scoredDirectory of Open Access Journals: No matching DOAJ record was present in this response. No allow-list match; this is not evidence of low credibility. Source: DOAJ; license: CC0
not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredROR affiliation: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
supportingOpen access status: Normalized open-access status: open. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
not scoredPublication license: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication version: A publication version was supplied but is not scored. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
cautionMetadata completeness: 5 of 6 scored descriptive metadata groups are present; missing fields increase uncertainty. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

Cite this work

BibTeX

@article{allodium:10.1158/2159-8290.cd-25-1454,
  title = {Blockade of Tumor-Intrinsic TGFβ Signaling Drives Hyperprogression in Small Cell Lung Cancer.},
  author = {Schroeder BA and Mohindroo C and Meinhardt AL and Takahashi N and Zhang Y and Lee MJ and Sahoo S and Donahue RN and Kumar R and Nirula M and Yang Y and Rastogi S and Sato N and Lee S and Tsai YT and Zhuang S and Kazi A and Huang Y and Desai P and Nichols S and Sciuto L and Pinkiert D and Chrisafis G and Greenberg M and Biery DN and Al-Marayaty R and Yang HH and Lee MP and Schultz CW and El Meskini R and Atkinson D and Fousek K and Gulley JL and Schlom J and Sato M and Shrestha RL and Sharma AK and Jolly MK and Palena C and Wakefield LM and Thomas A},
  year = {2026},
  journal = {Cancer discovery},
  doi = {10.1158/2159-8290.cd-25-1454},
  url = {https://doi.org/10.1158/2159-8290.cd-25-1454}
}

RIS

TY  - JOUR
TI  - Blockade of Tumor-Intrinsic TGFβ Signaling Drives Hyperprogression in Small Cell Lung Cancer.
AU  - Schroeder BA
AU  - Mohindroo C
AU  - Meinhardt AL
AU  - Takahashi N
AU  - Zhang Y
AU  - Lee MJ
AU  - Sahoo S
AU  - Donahue RN
AU  - Kumar R
AU  - Nirula M
AU  - Yang Y
AU  - Rastogi S
AU  - Sato N
AU  - Lee S
AU  - Tsai YT
AU  - Zhuang S
AU  - Kazi A
AU  - Huang Y
AU  - Desai P
AU  - Nichols S
AU  - Sciuto L
AU  - Pinkiert D
AU  - Chrisafis G
AU  - Greenberg M
AU  - Biery DN
AU  - Al-Marayaty R
AU  - Yang HH
AU  - Lee MP
AU  - Schultz CW
AU  - El Meskini R
AU  - Atkinson D
AU  - Fousek K
AU  - Gulley JL
AU  - Schlom J
AU  - Sato M
AU  - Shrestha RL
AU  - Sharma AK
AU  - Jolly MK
AU  - Palena C
AU  - Wakefield LM
AU  - Thomas A
PY  - 2026
JO  - Cancer discovery
DO  - 10.1158/2159-8290.cd-25-1454
UR  - https://doi.org/10.1158/2159-8290.cd-25-1454
ER  -

APA

BA, S., C, M., AL, M., N, T., Y, Z., MJ, L., S, S., RN, D., R, K., M, N., Y, Y., S, R., N, S., S, L., YT, T., S, Z., A, K., Y, H., P, D., S, N., L, S., D, P., G, C., M, G., DN, B., R, A., HH, Y., MP, L., CW, S., R, E. M., D, A., K, F., JL, G., J, S., M, S., RL, S., AK, S., MK, J., C, P., LM, W., & A, T. (2026). Blockade of Tumor-Intrinsic TGFβ Signaling Drives Hyperprogression in Small Cell Lung Cancer.. Cancer discovery. https://doi.org/10.1158/2159-8290.cd-25-1454

Source records

pubmed · retrieved 2026-09-26T22:07:35.490Z