An Inhaled Galectin-3 Inhibitor in COVID-19 Pneumonitis: A Phase Ib/IIa Randomized Controlled Clinical Trial (DEFINE).

Gaughan EE, Quinn TM, Mills A, Bruce AM, Antonelli J, MacKinnon AC, Aslanis V, Li F, O'Connor R, Boz C, Mills R, Emanuel P, Burgess M, Rinaldi G, Valanciute A, Mills B, Scholefield E, Hardisty G, Findlay EG, Parker RA, Norrie J, Dear JW, Akram AR, Koch O, Templeton K, Dockrell DH, Walsh TS, Partridge S, Humphries D, Wang-Jairaj J, Slack RJ, Schambye H, Phung, Gravelle L, Lindmark B, Shankar-Hari M, Hirani N, Sethi T, Dhaliwal K.

Open source

DOI: 10.1164/rccm.202203-0477oc
Published: 2023-01-01
Container: Am J Respir Crit Care Med
Publisher: Not recorded
Open access: yes

Credibility signals

limited evidence Score 45/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

cautionDOI registered: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
cautionDOI resolves: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
not scoredDirectory of Open Access Journals: No matching DOAJ record was present in this response. No allow-list match; this is not evidence of low credibility. Source: DOAJ; license: CC0
not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredROR affiliation: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
supportingOpen access status: Normalized open-access status: open. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
not scoredPublication license: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication version: A publication version was supplied but is not scored. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
cautionMetadata completeness: 5 of 6 scored descriptive metadata groups are present; missing fields increase uncertainty. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

Cite this work

BibTeX

@article{allodium:10.1164/rccm.202203-0477oc,
  title = {An Inhaled Galectin-3 Inhibitor in COVID-19 Pneumonitis: A Phase Ib/IIa Randomized Controlled Clinical Trial (DEFINE).},
  author = {Gaughan EE and  Quinn TM and  Mills A and  Bruce AM and  Antonelli J and  MacKinnon AC and  Aslanis V and  Li F and  O'Connor R and  Boz C and  Mills R and  Emanuel P and  Burgess M and  Rinaldi G and  Valanciute A and  Mills B and  Scholefield E and  Hardisty G and  Findlay EG and  Parker RA and  Norrie J and  Dear JW and  Akram AR and  Koch O and  Templeton K and  Dockrell DH and  Walsh TS and  Partridge S and  Humphries D and  Wang-Jairaj J and  Slack RJ and  Schambye H and  Phung and  Gravelle L and  Lindmark B and  Shankar-Hari M and  Hirani N and  Sethi T and  Dhaliwal K.},
  year = {2023},
  journal = {Am J Respir Crit Care Med},
  doi = {10.1164/rccm.202203-0477oc},
  url = {https://doi.org/10.1164/rccm.202203-0477oc}
}

RIS

TY  - JOUR
TI  - An Inhaled Galectin-3 Inhibitor in COVID-19 Pneumonitis: A Phase Ib/IIa Randomized Controlled Clinical Trial (DEFINE).
AU  - Gaughan EE
AU  -  Quinn TM
AU  -  Mills A
AU  -  Bruce AM
AU  -  Antonelli J
AU  -  MacKinnon AC
AU  -  Aslanis V
AU  -  Li F
AU  -  O'Connor R
AU  -  Boz C
AU  -  Mills R
AU  -  Emanuel P
AU  -  Burgess M
AU  -  Rinaldi G
AU  -  Valanciute A
AU  -  Mills B
AU  -  Scholefield E
AU  -  Hardisty G
AU  -  Findlay EG
AU  -  Parker RA
AU  -  Norrie J
AU  -  Dear JW
AU  -  Akram AR
AU  -  Koch O
AU  -  Templeton K
AU  -  Dockrell DH
AU  -  Walsh TS
AU  -  Partridge S
AU  -  Humphries D
AU  -  Wang-Jairaj J
AU  -  Slack RJ
AU  -  Schambye H
AU  -  Phung
AU  -  Gravelle L
AU  -  Lindmark B
AU  -  Shankar-Hari M
AU  -  Hirani N
AU  -  Sethi T
AU  -  Dhaliwal K.
PY  - 2023
JO  - Am J Respir Crit Care Med
DO  - 10.1164/rccm.202203-0477oc
UR  - https://doi.org/10.1164/rccm.202203-0477oc
ER  -

APA

EE, G., TM, Q., A, M., AM, B., J, A., AC, M., V, A., F, L., R, O., C, B., R, M., P, E., M, B., G, R., A, V., B, M., E, S., G, H., EG, F., RA, P., J, N., JW, D., AR, A., O, K., K, T., DH, D., TS, W., S, P., D, H., J, W., RJ, S., H, S., Phung, L, G., B, L., M, S., N, H., T, S., & K., D. (2023). An Inhaled Galectin-3 Inhibitor in COVID-19 Pneumonitis: A Phase Ib/IIa Randomized Controlled Clinical Trial (DEFINE).. Am J Respir Crit Care Med. https://doi.org/10.1164/rccm.202203-0477oc

Source records

europe-pmc · retrieved 2026-09-27T02:47:00.176Z