Stearoyl-CoA desaturase inhibition normalizes brain lipid saturation, α-synuclein homeostasis, and motor function in mutant Gba1-Parkinson mice

Silke Nuber, Harrison Hsiang, Esra’a Keewan, Tim E. Moors, Sydney J. Reitz, Anupama Tiwari, Gary P.H. Ho, Elena Su, Wolf Hahn, Marie-Alexandre Adom, Riddhima Pathak, Matthew Blizzard, Sangjune Kim, Han Seok Ko, Xiaoqun Zhang, Per Svenningsson, Dennis J. Selkoe, Saranna Fanning

Open source

DOI
10.1172/jci.insight.188413
Published
2025-06-03
Container
JCI Insight
Publisher
American Society for Clinical Investigation
Open access
unknown

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BibTeX

@article{allodium:10.1172/jci.insight.188413,
  title = {Stearoyl-CoA desaturase inhibition normalizes brain lipid saturation, α-synuclein homeostasis, and motor function in mutant Gba1-Parkinson mice},
  author = {Silke Nuber and Harrison Hsiang and Esra’a Keewan and Tim E. Moors and Sydney J. Reitz and Anupama Tiwari and Gary P.H. Ho and Elena Su and Wolf Hahn and Marie-Alexandre Adom and Riddhima Pathak and Matthew Blizzard and Sangjune Kim and Han Seok Ko and Xiaoqun Zhang and Per Svenningsson and Dennis J. Selkoe and Saranna Fanning},
  year = {2025},
  journal = {JCI Insight},
  doi = {10.1172/jci.insight.188413},
  url = {https://doi.org/10.1172/jci.insight.188413}
}

RIS

TY  - JOUR
TI  - Stearoyl-CoA desaturase inhibition normalizes brain lipid saturation, α-synuclein homeostasis, and motor function in mutant Gba1-Parkinson mice
AU  - Silke Nuber
AU  - Harrison Hsiang
AU  - Esra’a Keewan
AU  - Tim E. Moors
AU  - Sydney J. Reitz
AU  - Anupama Tiwari
AU  - Gary P.H. Ho
AU  - Elena Su
AU  - Wolf Hahn
AU  - Marie-Alexandre Adom
AU  - Riddhima Pathak
AU  - Matthew Blizzard
AU  - Sangjune Kim
AU  - Han Seok Ko
AU  - Xiaoqun Zhang
AU  - Per Svenningsson
AU  - Dennis J. Selkoe
AU  - Saranna Fanning
PY  - 2025
JO  - JCI Insight
DO  - 10.1172/jci.insight.188413
UR  - https://doi.org/10.1172/jci.insight.188413
ER  - 

APA

Nuber, S., Hsiang, H., Keewan, E., Moors, T. E., Reitz, S. J., Tiwari, A., Ho, G. P., Su, E., Hahn, W., Adom, M., Pathak, R., Blizzard, M., Kim, S., Ko, H. S., Zhang, X., Svenningsson, P., Selkoe, D. J., & Fanning, S. (2025). Stearoyl-CoA desaturase inhibition normalizes brain lipid saturation, α-synuclein homeostasis, and motor function in mutant Gba1-Parkinson mice. JCI Insight. https://doi.org/10.1172/jci.insight.188413

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