Glucosamine links hyperglycemia to mTORC1 activation and glucose toxicity in diabetes

Yael Riahi, Aviram Kogot-Levin, Ziv Teselpapa, Elisheva Zemelman, Fatema Gamal, Tamar Cohen, Abed Nasereddin, Idit Shiff, Ifat Abramovich, Bella Agranovich, Dana Avrahami, Liad Hinden, Erol Cerasi, Daljeet Kaur, Lihi Grinberg, Ron Piran, Joseph Tam, Ernesto Bernal-Mizrachi, Erez Dror, Gil Leibowitz

Open source

DOI: 10.1172/jci.insight.197331
Published: 2026-05-22
Container: JCI Insight
Publisher: American Society for Clinical Investigation
Open access: unknown

Credibility signals

uncertain Score 64/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

supportingDOI registered: A matching record was returned by Crossref. Source: Crossref; license: CC0 metadata
supportingDOI resolves: A matching record was returned by Crossref. Source: Crossref; license: CC0 metadata
not scoredDirectory of Open Access Journals: No matching DOAJ record was present in this response. No allow-list match; this is not evidence of low credibility. Source: DOAJ; license: CC0
not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredROR affiliation: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredOpen access status: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication license: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication version: A publication version was supplied but is not scored. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
supportingMetadata completeness: All 6 scored descriptive metadata groups are present. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

Cite this work

BibTeX

@article{allodium:10.1172/jci.insight.197331,
  title = {Glucosamine links hyperglycemia to mTORC1 activation and glucose toxicity in diabetes},
  author = {Yael Riahi and Aviram Kogot-Levin and Ziv Teselpapa and Elisheva Zemelman and Fatema Gamal and Tamar Cohen and Abed Nasereddin and Idit Shiff and Ifat Abramovich and Bella Agranovich and Dana Avrahami and Liad Hinden and Erol Cerasi and Daljeet Kaur and Lihi Grinberg and Ron Piran and Joseph Tam and Ernesto Bernal-Mizrachi and Erez Dror and Gil Leibowitz},
  year = {2026},
  journal = {JCI Insight},
  doi = {10.1172/jci.insight.197331},
  url = {https://doi.org/10.1172/jci.insight.197331}
}

RIS

TY  - JOUR
TI  - Glucosamine links hyperglycemia to mTORC1 activation and glucose toxicity in diabetes
AU  - Yael Riahi
AU  - Aviram Kogot-Levin
AU  - Ziv Teselpapa
AU  - Elisheva Zemelman
AU  - Fatema Gamal
AU  - Tamar Cohen
AU  - Abed Nasereddin
AU  - Idit Shiff
AU  - Ifat Abramovich
AU  - Bella Agranovich
AU  - Dana Avrahami
AU  - Liad Hinden
AU  - Erol Cerasi
AU  - Daljeet Kaur
AU  - Lihi Grinberg
AU  - Ron Piran
AU  - Joseph Tam
AU  - Ernesto Bernal-Mizrachi
AU  - Erez Dror
AU  - Gil Leibowitz
PY  - 2026
JO  - JCI Insight
DO  - 10.1172/jci.insight.197331
UR  - https://doi.org/10.1172/jci.insight.197331
ER  -

APA

Riahi, Y., Kogot-Levin, A., Teselpapa, Z., Zemelman, E., Gamal, F., Cohen, T., Nasereddin, A., Shiff, I., Abramovich, I., Agranovich, B., Avrahami, D., Hinden, L., Cerasi, E., Kaur, D., Grinberg, L., Piran, R., Tam, J., Bernal-Mizrachi, E., Dror, E., & Leibowitz, G. (2026). Glucosamine links hyperglycemia to mTORC1 activation and glucose toxicity in diabetes. JCI Insight. https://doi.org/10.1172/jci.insight.197331

Source records

crossref · retrieved 2026-09-26T11:20:21.556Z