JAK1/2 inhibition promotes aggressive cutaneous carcinogenesis through COT kinase–mediated alternative MAPK pathway activation

Hélène Pasquer, Antoine Forget, Maxime Battistella, Raphael Marie, Léa Provent, Barouyr Baroudjian, Emmanuelle Latour, Cécile Culeux, Blandine Roux, Khansa Saadallah, Amandine Gouverneur, Maxime Demourgues, Fanélie Jouenne, Jérôme Lambert, Bérangère Lombard, Damarys Loew, Sophie Tartare-Deckert, Lionel Adès, Emmanuel Raffoux, Bruno Cassinat, Juliette Soret-Dulphy, Pernelle Noize, Samia Mourah, Camille Lobry, Jean-Jacques Kiladjian, Alexandre Puissant, Céleste Lebbé, Lina Benajiba

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DOI: 10.1172/jci199141
Published: 2026-11-02
Container: Journal of Clinical Investigation
Publisher: American Society for Clinical Investigation
Open access: unknown

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Cite this work

BibTeX

@article{allodium:10.1172/jci199141,
  title = {JAK1/2 inhibition promotes aggressive cutaneous carcinogenesis through COT kinase–mediated alternative MAPK pathway activation},
  author = {Hélène Pasquer and Antoine Forget and Maxime Battistella and Raphael Marie and Léa Provent and Barouyr Baroudjian and Emmanuelle Latour and Cécile Culeux and Blandine Roux and Khansa Saadallah and Amandine Gouverneur and Maxime Demourgues and Fanélie Jouenne and Jérôme Lambert and Bérangère Lombard and Damarys Loew and Sophie Tartare-Deckert and Lionel Adès and Emmanuel Raffoux and Bruno Cassinat and Juliette Soret-Dulphy and Pernelle Noize and Samia Mourah and Camille Lobry and Jean-Jacques Kiladjian and Alexandre Puissant and Céleste Lebbé and Lina Benajiba},
  year = {2026},
  journal = {Journal of Clinical Investigation},
  doi = {10.1172/jci199141},
  url = {https://doi.org/10.1172/jci199141}
}

RIS

TY  - JOUR
TI  - JAK1/2 inhibition promotes aggressive cutaneous carcinogenesis through COT kinase–mediated alternative MAPK pathway activation
AU  - Hélène Pasquer
AU  - Antoine Forget
AU  - Maxime Battistella
AU  - Raphael Marie
AU  - Léa Provent
AU  - Barouyr Baroudjian
AU  - Emmanuelle Latour
AU  - Cécile Culeux
AU  - Blandine Roux
AU  - Khansa Saadallah
AU  - Amandine Gouverneur
AU  - Maxime Demourgues
AU  - Fanélie Jouenne
AU  - Jérôme Lambert
AU  - Bérangère Lombard
AU  - Damarys Loew
AU  - Sophie Tartare-Deckert
AU  - Lionel Adès
AU  - Emmanuel Raffoux
AU  - Bruno Cassinat
AU  - Juliette Soret-Dulphy
AU  - Pernelle Noize
AU  - Samia Mourah
AU  - Camille Lobry
AU  - Jean-Jacques Kiladjian
AU  - Alexandre Puissant
AU  - Céleste Lebbé
AU  - Lina Benajiba
PY  - 2026
JO  - Journal of Clinical Investigation
DO  - 10.1172/jci199141
UR  - https://doi.org/10.1172/jci199141
ER  -

APA

Pasquer, H., Forget, A., Battistella, M., Marie, R., Provent, L., Baroudjian, B., Latour, E., Culeux, C., Roux, B., Saadallah, K., Gouverneur, A., Demourgues, M., Jouenne, F., Lambert, J., Lombard, B., Loew, D., Tartare-Deckert, S., Adès, L., Raffoux, E., Cassinat, B., Soret-Dulphy, J., Noize, P., Mourah, S., Lobry, C., Kiladjian, J., Puissant, A., Lebbé, C., & Benajiba, L. (2026). JAK1/2 inhibition promotes aggressive cutaneous carcinogenesis through COT kinase–mediated alternative MAPK pathway activation. Journal of Clinical Investigation. https://doi.org/10.1172/jci199141

Source records

crossref · retrieved 2026-11-04T09:38:16.530Z