SLC15A3-mediated dipeptide metabolism confers antimetabolite resistance in lymphoma via mTORC1 activation

Haojun Yang, Vincenzo Andrea Zingaro, Kevin Boardman, Ashish Noronha, Ekin Guney, Lingru Xue, Saishma Hoigebazar, Isabelle Liu, Sohit Miglani, Siyu Chen, Hieu Vu, Kwun Wah Wen, Hao G. Nguyen, Hani Goodarzi, Ralph J. DeBerardinis, Davide Ruggero

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DOI: 10.1172/jci199709
Published: 2026-07-15
Container: Journal of Clinical Investigation
Publisher: American Society for Clinical Investigation
Open access: unknown

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Cite this work

BibTeX

@article{allodium:10.1172/jci199709,
  title = {SLC15A3-mediated dipeptide metabolism confers antimetabolite resistance in lymphoma via mTORC1 activation},
  author = {Haojun Yang and Vincenzo Andrea Zingaro and Kevin Boardman and Ashish Noronha and Ekin Guney and Lingru Xue and Saishma Hoigebazar and Isabelle Liu and Sohit Miglani and Siyu Chen and Hieu Vu and Kwun Wah Wen and Hao G. Nguyen and Hani Goodarzi and Ralph J. DeBerardinis and Davide Ruggero},
  year = {2026},
  journal = {Journal of Clinical Investigation},
  doi = {10.1172/jci199709},
  url = {https://doi.org/10.1172/jci199709}
}

RIS

TY  - JOUR
TI  - SLC15A3-mediated dipeptide metabolism confers antimetabolite resistance in lymphoma via mTORC1 activation
AU  - Haojun Yang
AU  - Vincenzo Andrea Zingaro
AU  - Kevin Boardman
AU  - Ashish Noronha
AU  - Ekin Guney
AU  - Lingru Xue
AU  - Saishma Hoigebazar
AU  - Isabelle Liu
AU  - Sohit Miglani
AU  - Siyu Chen
AU  - Hieu Vu
AU  - Kwun Wah Wen
AU  - Hao G. Nguyen
AU  - Hani Goodarzi
AU  - Ralph J. DeBerardinis
AU  - Davide Ruggero
PY  - 2026
JO  - Journal of Clinical Investigation
DO  - 10.1172/jci199709
UR  - https://doi.org/10.1172/jci199709
ER  -

APA

Yang, H., Zingaro, V. A., Boardman, K., Noronha, A., Guney, E., Xue, L., Hoigebazar, S., Liu, I., Miglani, S., Chen, S., Vu, H., Wen, K. W., Nguyen, H. G., Goodarzi, H., DeBerardinis, R. J., & Ruggero, D. (2026). SLC15A3-mediated dipeptide metabolism confers antimetabolite resistance in lymphoma via mTORC1 activation. Journal of Clinical Investigation. https://doi.org/10.1172/jci199709

Source records

crossref · retrieved 2026-09-25T20:36:33.948Z