Lymphocyte count polygenicity underlies dimethyl fumarate-associated lymphopenia in multiple sclerosis.

Kowalec K, Manouchehrinia A, Kingwell E, Carruthers R, Marrie RA, Evans C, Rotstein D, Kuan AJ, Luo W, Luo D, Desrochers B, Jokubaitis VG, Lechner-Scott J, Maltby VE, Groen K, Wright GE, Drögemöller BI, Bernatsky S, Levin MC, Knox K, Maruf AA, Zhong M, Alfredsson L, Hillert J, Kockum I, Olsson T, Stridh P, Shchetynsky K, Dever K, MacIsaac J, Kobor MS, Tremlett H

Open source

DOI: 10.1177/13524585261471335
Published: 2026 Aug 17
Container: Multiple sclerosis (Houndmills, Basingstoke, England)
Publisher: Not recorded
Open access: unknown

Credibility signals

limited evidence Score 43/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

cautionDOI registered: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
cautionDOI resolves: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
not scoredDirectory of Open Access Journals: No matching DOAJ record was present in this response. No allow-list match; this is not evidence of low credibility. Source: DOAJ; license: CC0
not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredROR affiliation: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredOpen access status: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication license: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication version: A publication version was supplied but is not scored. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
cautionMetadata completeness: 5 of 6 scored descriptive metadata groups are present; missing fields increase uncertainty. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

Cite this work

BibTeX

@article{allodium:10.1177/13524585261471335,
  title = {Lymphocyte count polygenicity underlies dimethyl fumarate-associated lymphopenia in multiple sclerosis.},
  author = {Kowalec K and Manouchehrinia A and Kingwell E and Carruthers R and Marrie RA and Evans C and Rotstein D and Kuan AJ and Luo W and Luo D and Desrochers B and Jokubaitis VG and Lechner-Scott J and Maltby VE and Groen K and Wright GE and Drögemöller BI and Bernatsky S and Levin MC and Knox K and Maruf AA and Zhong M and Alfredsson L and Hillert J and Kockum I and Olsson T and Stridh P and Shchetynsky K and Dever K and MacIsaac J and Kobor MS and Tremlett H},
  year = {2026},
  journal = {Multiple sclerosis (Houndmills, Basingstoke, England)},
  doi = {10.1177/13524585261471335},
  url = {https://doi.org/10.1177/13524585261471335}
}

RIS

TY  - JOUR
TI  - Lymphocyte count polygenicity underlies dimethyl fumarate-associated lymphopenia in multiple sclerosis.
AU  - Kowalec K
AU  - Manouchehrinia A
AU  - Kingwell E
AU  - Carruthers R
AU  - Marrie RA
AU  - Evans C
AU  - Rotstein D
AU  - Kuan AJ
AU  - Luo W
AU  - Luo D
AU  - Desrochers B
AU  - Jokubaitis VG
AU  - Lechner-Scott J
AU  - Maltby VE
AU  - Groen K
AU  - Wright GE
AU  - Drögemöller BI
AU  - Bernatsky S
AU  - Levin MC
AU  - Knox K
AU  - Maruf AA
AU  - Zhong M
AU  - Alfredsson L
AU  - Hillert J
AU  - Kockum I
AU  - Olsson T
AU  - Stridh P
AU  - Shchetynsky K
AU  - Dever K
AU  - MacIsaac J
AU  - Kobor MS
AU  - Tremlett H
PY  - 2026
JO  - Multiple sclerosis (Houndmills, Basingstoke, England)
DO  - 10.1177/13524585261471335
UR  - https://doi.org/10.1177/13524585261471335
ER  -

APA

K, K., A, M., E, K., R, C., RA, M., C, E., D, R., AJ, K., W, L., D, L., B, D., VG, J., J, L., VE, M., K, G., GE, W., BI, D., S, B., MC, L., K, K., AA, M., M, Z., L, A., J, H., I, K., T, O., P, S., K, S., K, D., J, M., MS, K., & H, T. (2026). Lymphocyte count polygenicity underlies dimethyl fumarate-associated lymphopenia in multiple sclerosis.. Multiple sclerosis (Houndmills, Basingstoke, England). https://doi.org/10.1177/13524585261471335

Source records

pubmed · retrieved 2026-09-26T08:59:58.293Z