Efficacy of a novel BCL-xL degrader, DT2216, in preclinical models of JAK2-mutated post-MPN AML.

Wang Z, Skwarska A, Poigaialwar G, Chaudhry S, Rodriguez-Meira A, Sui P, Olivier E, Jia Y, Gupta V, Fiskus W, Ramage CL, Zheng G, Schurer A, Gritsman K, Papapetrou EP, Bhalla K, Zhou D, Mead AJ, Rampal RK, Tyner JW, Abbas HA, Pemmaraju N, Tatarata QZ, Konopleva M

Open source

DOI: 10.1182/blood.2024027117
Published: 2025 Jul 17
Container: Blood
Publisher: Not recorded
Open access: yes

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Cite this work

BibTeX

@article{allodium:10.1182/blood.2024027117,
  title = {Efficacy of a novel BCL-xL degrader, DT2216, in preclinical models of JAK2-mutated post-MPN AML.},
  author = {Wang Z and Skwarska A and Poigaialwar G and Chaudhry S and Rodriguez-Meira A and Sui P and Olivier E and Jia Y and Gupta V and Fiskus W and Ramage CL and Zheng G and Schurer A and Gritsman K and Papapetrou EP and Bhalla K and Zhou D and Mead AJ and Rampal RK and Tyner JW and Abbas HA and Pemmaraju N and Tatarata QZ and Konopleva M},
  year = {2025},
  journal = {Blood},
  doi = {10.1182/blood.2024027117},
  url = {https://doi.org/10.1182/blood.2024027117}
}

RIS

TY  - JOUR
TI  - Efficacy of a novel BCL-xL degrader, DT2216, in preclinical models of JAK2-mutated post-MPN AML.
AU  - Wang Z
AU  - Skwarska A
AU  - Poigaialwar G
AU  - Chaudhry S
AU  - Rodriguez-Meira A
AU  - Sui P
AU  - Olivier E
AU  - Jia Y
AU  - Gupta V
AU  - Fiskus W
AU  - Ramage CL
AU  - Zheng G
AU  - Schurer A
AU  - Gritsman K
AU  - Papapetrou EP
AU  - Bhalla K
AU  - Zhou D
AU  - Mead AJ
AU  - Rampal RK
AU  - Tyner JW
AU  - Abbas HA
AU  - Pemmaraju N
AU  - Tatarata QZ
AU  - Konopleva M
PY  - 2025
JO  - Blood
DO  - 10.1182/blood.2024027117
UR  - https://doi.org/10.1182/blood.2024027117
ER  -

APA

Z, W., A, S., G, P., S, C., A, R., P, S., E, O., Y, J., V, G., W, F., CL, R., G, Z., A, S., K, G., EP, P., K, B., D, Z., AJ, M., RK, R., JW, T., HA, A., N, P., QZ, T., & M, K. (2025). Efficacy of a novel BCL-xL degrader, DT2216, in preclinical models of JAK2-mutated post-MPN AML.. Blood. https://doi.org/10.1182/blood.2024027117

Source records

pubmed · retrieved 2026-09-25T18:38:31.865Z