Silencing of PAI-1 using siRNA-lipid nanoparticles reduces thrombosis and prolongs life span in murine models.

Ferraresso F, Skaer CW, Wei Z, Hur WS, Yu H, Seadler M, Chen THY, Dai W, Paul M, Lapointe C, Ketelboeter LM, Lund H, Rodriguez GG, Juang LJ, Strilchuk AW, Zhang Y, Cullis PR, Dyer MR, Gerras AL, Shi Q, Luyendyk JP, Flick MJ, Zheng Z, Kastrup CJ

Open source

DOI: 10.1182/blood.2025029834
Published: 2026 Apr 30
Container: Blood
Publisher: Not recorded
Open access: yes

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Cite this work

BibTeX

@article{allodium:10.1182/blood.2025029834,
  title = {Silencing of PAI-1 using siRNA-lipid nanoparticles reduces thrombosis and prolongs life span in murine models.},
  author = {Ferraresso F and Skaer CW and Wei Z and Hur WS and Yu H and Seadler M and Chen THY and Dai W and Paul M and Lapointe C and Ketelboeter LM and Lund H and Rodriguez GG and Juang LJ and Strilchuk AW and Zhang Y and Cullis PR and Dyer MR and Gerras AL and Shi Q and Luyendyk JP and Flick MJ and Zheng Z and Kastrup CJ},
  year = {2026},
  journal = {Blood},
  doi = {10.1182/blood.2025029834},
  url = {https://doi.org/10.1182/blood.2025029834}
}

RIS

TY  - JOUR
TI  - Silencing of PAI-1 using siRNA-lipid nanoparticles reduces thrombosis and prolongs life span in murine models.
AU  - Ferraresso F
AU  - Skaer CW
AU  - Wei Z
AU  - Hur WS
AU  - Yu H
AU  - Seadler M
AU  - Chen THY
AU  - Dai W
AU  - Paul M
AU  - Lapointe C
AU  - Ketelboeter LM
AU  - Lund H
AU  - Rodriguez GG
AU  - Juang LJ
AU  - Strilchuk AW
AU  - Zhang Y
AU  - Cullis PR
AU  - Dyer MR
AU  - Gerras AL
AU  - Shi Q
AU  - Luyendyk JP
AU  - Flick MJ
AU  - Zheng Z
AU  - Kastrup CJ
PY  - 2026
JO  - Blood
DO  - 10.1182/blood.2025029834
UR  - https://doi.org/10.1182/blood.2025029834
ER  -

APA

F, F., CW, S., Z, W., WS, H., H, Y., M, S., THY, C., W, D., M, P., C, L., LM, K., H, L., GG, R., LJ, J., AW, S., Y, Z., PR, C., MR, D., AL, G., Q, S., JP, L., MJ, F., Z, Z., & CJ, K. (2026). Silencing of PAI-1 using siRNA-lipid nanoparticles reduces thrombosis and prolongs life span in murine models.. Blood. https://doi.org/10.1182/blood.2025029834

Source records

pubmed · retrieved 2026-09-26T13:17:15.404Z
europe-pmc · retrieved 2026-09-26T13:17:15.400Z