RAG1 lentiviral gene therapy restores T-cell development of RAG1-SCID patient cells in artificial thymic organoids.

Meng X, Melsen JE, van der Holst R, de Mooij B, Vloemans S, van Eggermond M, Berghuis D, Lankester AC, de Kivit S, Pike-Overzet K, Langerak AW, Staal FJT, Ott de Bruin LM, Canté-Barrett K

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DOI: 10.1182/bloodadvances.2025016970
Published: 2025 Nov 25
Container: Blood advances
Publisher: Not recorded
Open access: yes

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Cite this work

BibTeX

@article{allodium:10.1182/bloodadvances.2025016970,
  title = {RAG1 lentiviral gene therapy restores T-cell development of RAG1-SCID patient cells in artificial thymic organoids.},
  author = {Meng X and Melsen JE and van der Holst R and de Mooij B and Vloemans S and van Eggermond M and Berghuis D and Lankester AC and de Kivit S and Pike-Overzet K and Langerak AW and Staal FJT and Ott de Bruin LM and Canté-Barrett K},
  year = {2025},
  journal = {Blood advances},
  doi = {10.1182/bloodadvances.2025016970},
  url = {https://doi.org/10.1182/bloodadvances.2025016970}
}

RIS

TY  - JOUR
TI  - RAG1 lentiviral gene therapy restores T-cell development of RAG1-SCID patient cells in artificial thymic organoids.
AU  - Meng X
AU  - Melsen JE
AU  - van der Holst R
AU  - de Mooij B
AU  - Vloemans S
AU  - van Eggermond M
AU  - Berghuis D
AU  - Lankester AC
AU  - de Kivit S
AU  - Pike-Overzet K
AU  - Langerak AW
AU  - Staal FJT
AU  - Ott de Bruin LM
AU  - Canté-Barrett K
PY  - 2025
JO  - Blood advances
DO  - 10.1182/bloodadvances.2025016970
UR  - https://doi.org/10.1182/bloodadvances.2025016970
ER  -

APA

X, M., JE, M., R, V. D. H., B, D. M., S, V., M, V. E., D, B., AC, L., S, D. K., K, P., AW, L., FJT, S., LM, O. D. B., & K, C. (2025). RAG1 lentiviral gene therapy restores T-cell development of RAG1-SCID patient cells in artificial thymic organoids.. Blood advances. https://doi.org/10.1182/bloodadvances.2025016970

Source records

pubmed · retrieved 2026-09-26T09:46:17.547Z