Safety and efficacy of upfront triple therapy including parenteral treprostinil compared to double oral therapy in PAH (TripleTRE): study protocol for a randomised trial.

Sitbon O, Agoston G, Badagliacca R, Hajnalka Balint O, Blanco I, Coman IM, Ewert R, Halank M, Jansa P, Kopeć G, Kurzyna M, Tenes A, Opitz C, Plácido R, Přeček J, Riou M, Steringer-Mascherbauer R, Țilea I, Lang IM

Open source

DOI
10.1183/23120541.00458-2025
Published
2026 Jan
Container
ERJ open research
Publisher
Not recorded
Open access
yes

Credibility signals

limited evidence Score 45/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

Cite this work

BibTeX

@article{allodium:10.1183/23120541.00458-2025,
  title = {Safety and efficacy of upfront triple therapy including parenteral treprostinil compared to double oral therapy in PAH (TripleTRE): study protocol for a randomised trial.},
  author = {Sitbon O and Agoston G and Badagliacca R and Hajnalka Balint O and Blanco I and Coman IM and Ewert R and Halank M and Jansa P and Kopeć G and Kurzyna M and Tenes A and Opitz C and Plácido R and Přeček J and Riou M and Steringer-Mascherbauer R and Țilea I and Lang IM},
  year = {2026},
  journal = {ERJ open research},
  doi = {10.1183/23120541.00458-2025},
  url = {https://doi.org/10.1183/23120541.00458-2025}
}

RIS

TY  - JOUR
TI  - Safety and efficacy of upfront triple therapy including parenteral treprostinil compared to double oral therapy in PAH (TripleTRE): study protocol for a randomised trial.
AU  - Sitbon O
AU  - Agoston G
AU  - Badagliacca R
AU  - Hajnalka Balint O
AU  - Blanco I
AU  - Coman IM
AU  - Ewert R
AU  - Halank M
AU  - Jansa P
AU  - Kopeć G
AU  - Kurzyna M
AU  - Tenes A
AU  - Opitz C
AU  - Plácido R
AU  - Přeček J
AU  - Riou M
AU  - Steringer-Mascherbauer R
AU  - Țilea I
AU  - Lang IM
PY  - 2026
JO  - ERJ open research
DO  - 10.1183/23120541.00458-2025
UR  - https://doi.org/10.1183/23120541.00458-2025
ER  - 

APA

O, S., G, A., R, B., O, H. B., I, B., IM, C., R, E., M, H., P, J., G, K., M, K., A, T., C, O., R, P., J, P., M, R., R, S., I, Ț., & IM, L. (2026). Safety and efficacy of upfront triple therapy including parenteral treprostinil compared to double oral therapy in PAH (TripleTRE): study protocol for a randomised trial.. ERJ open research. https://doi.org/10.1183/23120541.00458-2025

Source records