CD64 binding potential does not translate into enhanced therapeutic efficacy for anti-IL-23 antibodies under physiologically relevant conditions

Joel F. Cohen-Solal, Calvin S. Pohl, Sheila M. Cummings, Jeremy P. Gygi, Zhaleh Safikhani, Brigitte Bartocha, Christopher D. Buckley, Yongli Dong, Killian Eyerich, Samuel D. Karsen, Grace R. Lynch, Michael Macoritto, Pierre A. Morisset, Ornella D. Nelson, Timothy Radstake, Florian Rieder, Jocelyn Rivas, John P. Savaryn, Kathleen M. Smith, Madison Stulir, Carmin Szynal, Casey Tylek, Geertruida M. Veldman, Laura G. Wasserman, Susan Westmoreland, Neha Chaudhary, Matthew M. Staron

Open source

DOI
10.1186/s10020-026-01462-z
Published
2026-03-28
Container
Molecular Medicine
Publisher
Springer Science and Business Media LLC
Open access
unknown

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BibTeX

@article{allodium:10.1186/s10020-026-01462-z,
  title = {CD64 binding potential does not translate into enhanced therapeutic efficacy for anti-IL-23 antibodies under physiologically relevant conditions},
  author = {Joel F. Cohen-Solal and Calvin S. Pohl and Sheila M. Cummings and Jeremy P. Gygi and Zhaleh Safikhani and Brigitte Bartocha and Christopher D. Buckley and Yongli Dong and Killian Eyerich and Samuel D. Karsen and Grace R. Lynch and Michael Macoritto and Pierre A. Morisset and Ornella D. Nelson and Timothy Radstake and Florian Rieder and Jocelyn Rivas and John P. Savaryn and Kathleen M. Smith and Madison Stulir and Carmin Szynal and Casey Tylek and Geertruida M. Veldman and Laura G. Wasserman and Susan Westmoreland and Neha Chaudhary and Matthew M. Staron},
  year = {2026},
  journal = {Molecular Medicine},
  doi = {10.1186/s10020-026-01462-z},
  url = {https://doi.org/10.1186/s10020-026-01462-z}
}

RIS

TY  - JOUR
TI  - CD64 binding potential does not translate into enhanced therapeutic efficacy for anti-IL-23 antibodies under physiologically relevant conditions
AU  - Joel F. Cohen-Solal
AU  - Calvin S. Pohl
AU  - Sheila M. Cummings
AU  - Jeremy P. Gygi
AU  - Zhaleh Safikhani
AU  - Brigitte Bartocha
AU  - Christopher D. Buckley
AU  - Yongli Dong
AU  - Killian Eyerich
AU  - Samuel D. Karsen
AU  - Grace R. Lynch
AU  - Michael Macoritto
AU  - Pierre A. Morisset
AU  - Ornella D. Nelson
AU  - Timothy Radstake
AU  - Florian Rieder
AU  - Jocelyn Rivas
AU  - John P. Savaryn
AU  - Kathleen M. Smith
AU  - Madison Stulir
AU  - Carmin Szynal
AU  - Casey Tylek
AU  - Geertruida M. Veldman
AU  - Laura G. Wasserman
AU  - Susan Westmoreland
AU  - Neha Chaudhary
AU  - Matthew M. Staron
PY  - 2026
JO  - Molecular Medicine
DO  - 10.1186/s10020-026-01462-z
UR  - https://doi.org/10.1186/s10020-026-01462-z
ER  - 

APA

Cohen-Solal, J. F., Pohl, C. S., Cummings, S. M., Gygi, J. P., Safikhani, Z., Bartocha, B., Buckley, C. D., Dong, Y., Eyerich, K., Karsen, S. D., Lynch, G. R., Macoritto, M., Morisset, P. A., Nelson, O. D., Radstake, T., Rieder, F., Rivas, J., Savaryn, J. P., Smith, K. M., Stulir, M., Szynal, C., Tylek, C., Veldman, G. M., Wasserman, L. G., Westmoreland, S., Chaudhary, N., & Staron, M. M. (2026). CD64 binding potential does not translate into enhanced therapeutic efficacy for anti-IL-23 antibodies under physiologically relevant conditions. Molecular Medicine. https://doi.org/10.1186/s10020-026-01462-z

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