Using skin biopsies to measure target occupancy of anti-fibrotic molecules: assay development and application for zampilimab in a primate model of chronic kidney disease and in healthy human volunteers

Linghong Huang, Rowann Bowcutt, Alison Bigley, Graham Ogg, Tim Schmidt, Geoffrey I. Johnston, Timothy S. Johnson

Open source

DOI
10.1186/s12882-025-04467-8
Published
2025-11-21
Container
BMC Nephrology
Publisher
Springer Science and Business Media LLC
Open access
unknown

Credibility signals

uncertain Score 64/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

Cite this work

BibTeX

@article{allodium:10.1186/s12882-025-04467-8,
  title = {Using skin biopsies to measure target occupancy of anti-fibrotic molecules: assay development and application for zampilimab in a primate model of chronic kidney disease and in healthy human volunteers},
  author = {Linghong Huang and Rowann Bowcutt and Alison Bigley and Graham Ogg and Tim Schmidt and Geoffrey I. Johnston and Timothy S. Johnson},
  year = {2025},
  journal = {BMC Nephrology},
  doi = {10.1186/s12882-025-04467-8},
  url = {https://doi.org/10.1186/s12882-025-04467-8}
}

RIS

TY  - JOUR
TI  - Using skin biopsies to measure target occupancy of anti-fibrotic molecules: assay development and application for zampilimab in a primate model of chronic kidney disease and in healthy human volunteers
AU  - Linghong Huang
AU  - Rowann Bowcutt
AU  - Alison Bigley
AU  - Graham Ogg
AU  - Tim Schmidt
AU  - Geoffrey I. Johnston
AU  - Timothy S. Johnson
PY  - 2025
JO  - BMC Nephrology
DO  - 10.1186/s12882-025-04467-8
UR  - https://doi.org/10.1186/s12882-025-04467-8
ER  - 

APA

Huang, L., Bowcutt, R., Bigley, A., Ogg, G., Schmidt, T., Johnston, G. I., & Johnson, T. S. (2025). Using skin biopsies to measure target occupancy of anti-fibrotic molecules: assay development and application for zampilimab in a primate model of chronic kidney disease and in healthy human volunteers. BMC Nephrology. https://doi.org/10.1186/s12882-025-04467-8

Source records