Rationale and design of a multicenter placebo-controlled double-blind randomized trial to evaluate the effect of empagliflozin on endothelial function: the EMBLEM trial

Atsushi Tanaka, Michio Shimabukuro, Yosuke Okada, Isao Taguchi, Minako Yamaoka-Tojo, Hirofumi Tomiyama, Hiroki Teragawa, Seigo Sugiyama, Hisako Yoshida, Yasunori Sato, Atsushi Kawaguchi, Yumi Ikehara, Noritaka Machii, Tatsuya Maruhashi, Kosuke R. Shima, Toshinari Takamura, Yasushi Matsuzawa, Kazuo Kimura, Masashi Sakuma, Jun-ichi Oyama, Teruo Inoue, Yukihito Higashi, Shinichiro Ueda, Koichi Node, Unknown

Open source

DOI: 10.1186/s12933-017-0532-8
Published: 2017-04-12
Container: Cardiovascular Diabetology
Publisher: Springer Science and Business Media LLC
Open access: unknown

Credibility signals

uncertain Score 64/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

supportingDOI registered: A matching record was returned by Crossref. Source: Crossref; license: CC0 metadata
supportingDOI resolves: A matching record was returned by Crossref. Source: Crossref; license: CC0 metadata
not scoredDirectory of Open Access Journals: No matching DOAJ record was present in this response. No allow-list match; this is not evidence of low credibility. Source: DOAJ; license: CC0
not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredROR affiliation: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredOpen access status: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication license: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication version: A publication version was supplied but is not scored. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
supportingMetadata completeness: All 6 scored descriptive metadata groups are present. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

Cite this work

BibTeX

@article{allodium:10.1186/s12933-017-0532-8,
  title = {Rationale and design of a multicenter placebo-controlled double-blind randomized trial to evaluate the effect of empagliflozin on endothelial function: the EMBLEM trial},
  author = {Atsushi Tanaka and Michio Shimabukuro and Yosuke Okada and Isao Taguchi and Minako Yamaoka-Tojo and Hirofumi Tomiyama and Hiroki Teragawa and Seigo Sugiyama and Hisako Yoshida and Yasunori Sato and Atsushi Kawaguchi and Yumi Ikehara and Noritaka Machii and Tatsuya Maruhashi and Kosuke R. Shima and Toshinari Takamura and Yasushi Matsuzawa and Kazuo Kimura and Masashi Sakuma and Jun-ichi Oyama and Teruo Inoue and Yukihito Higashi and Shinichiro Ueda and Koichi Node and Unknown},
  year = {2017},
  journal = {Cardiovascular Diabetology},
  doi = {10.1186/s12933-017-0532-8},
  url = {https://doi.org/10.1186/s12933-017-0532-8}
}

RIS

TY  - JOUR
TI  - Rationale and design of a multicenter placebo-controlled double-blind randomized trial to evaluate the effect of empagliflozin on endothelial function: the EMBLEM trial
AU  - Atsushi Tanaka
AU  - Michio Shimabukuro
AU  - Yosuke Okada
AU  - Isao Taguchi
AU  - Minako Yamaoka-Tojo
AU  - Hirofumi Tomiyama
AU  - Hiroki Teragawa
AU  - Seigo Sugiyama
AU  - Hisako Yoshida
AU  - Yasunori Sato
AU  - Atsushi Kawaguchi
AU  - Yumi Ikehara
AU  - Noritaka Machii
AU  - Tatsuya Maruhashi
AU  - Kosuke R. Shima
AU  - Toshinari Takamura
AU  - Yasushi Matsuzawa
AU  - Kazuo Kimura
AU  - Masashi Sakuma
AU  - Jun-ichi Oyama
AU  - Teruo Inoue
AU  - Yukihito Higashi
AU  - Shinichiro Ueda
AU  - Koichi Node
AU  - Unknown
PY  - 2017
JO  - Cardiovascular Diabetology
DO  - 10.1186/s12933-017-0532-8
UR  - https://doi.org/10.1186/s12933-017-0532-8
ER  -

APA

Tanaka, A., Shimabukuro, M., Okada, Y., Taguchi, I., Yamaoka-Tojo, M., Tomiyama, H., Teragawa, H., Sugiyama, S., Yoshida, H., Sato, Y., Kawaguchi, A., Ikehara, Y., Machii, N., Maruhashi, T., Shima, K. R., Takamura, T., Matsuzawa, Y., Kimura, K., Sakuma, M., Oyama, J., Inoue, T., Higashi, Y., Ueda, S., Node, K., & Unknown (2017). Rationale and design of a multicenter placebo-controlled double-blind randomized trial to evaluate the effect of empagliflozin on endothelial function: the EMBLEM trial. Cardiovascular Diabetology. https://doi.org/10.1186/s12933-017-0532-8

Source records

crossref · retrieved 2026-09-27T08:38:48.559Z