In silico screening, synthesis, and biological evaluation of pyrazolopyrimidine-derived mTOR inhibitors for anticancer and senomorphic effects

David Rysanek, Zofia Chrienova, Dorota Stary, Marek Bajda, Josef Novak, Pavla Vasicova, Jirina Kroupova, Rudolf Andrys, Adam Skarka, Erika Rousarova, Jan Capek, Tomas Rousar, Zoran Milovanovic, Jelica Grujic-Milanovic, Vesna Jacevic, Jayaprakash N. Kolla, Martin Popr, Dominika Maurencova, Patrik Oleksak, Lukas Fresser, Kamil Kuca, Zdenek Hodny, Eugenie Nepovimova

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DOI: 10.1186/s12935-026-04308-0
Published: 2026-05-06
Container: Cancer Cell International
Publisher: Springer Science and Business Media LLC
Open access: unknown

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Cite this work

BibTeX

@article{allodium:10.1186/s12935-026-04308-0,
  title = {In silico screening, synthesis, and biological evaluation of pyrazolopyrimidine-derived mTOR inhibitors for anticancer and senomorphic effects},
  author = {David Rysanek and Zofia Chrienova and Dorota Stary and Marek Bajda and Josef Novak and Pavla Vasicova and Jirina Kroupova and Rudolf Andrys and Adam Skarka and Erika Rousarova and Jan Capek and Tomas Rousar and Zoran Milovanovic and Jelica Grujic-Milanovic and Vesna Jacevic and Jayaprakash N. Kolla and Martin Popr and Dominika Maurencova and Patrik Oleksak and Lukas Fresser and Kamil Kuca and Zdenek Hodny and Eugenie Nepovimova},
  year = {2026},
  journal = {Cancer Cell International},
  doi = {10.1186/s12935-026-04308-0},
  url = {https://doi.org/10.1186/s12935-026-04308-0}
}

RIS

TY  - JOUR
TI  - In silico screening, synthesis, and biological evaluation of pyrazolopyrimidine-derived mTOR inhibitors for anticancer and senomorphic effects
AU  - David Rysanek
AU  - Zofia Chrienova
AU  - Dorota Stary
AU  - Marek Bajda
AU  - Josef Novak
AU  - Pavla Vasicova
AU  - Jirina Kroupova
AU  - Rudolf Andrys
AU  - Adam Skarka
AU  - Erika Rousarova
AU  - Jan Capek
AU  - Tomas Rousar
AU  - Zoran Milovanovic
AU  - Jelica Grujic-Milanovic
AU  - Vesna Jacevic
AU  - Jayaprakash N. Kolla
AU  - Martin Popr
AU  - Dominika Maurencova
AU  - Patrik Oleksak
AU  - Lukas Fresser
AU  - Kamil Kuca
AU  - Zdenek Hodny
AU  - Eugenie Nepovimova
PY  - 2026
JO  - Cancer Cell International
DO  - 10.1186/s12935-026-04308-0
UR  - https://doi.org/10.1186/s12935-026-04308-0
ER  -

APA

Rysanek, D., Chrienova, Z., Stary, D., Bajda, M., Novak, J., Vasicova, P., Kroupova, J., Andrys, R., Skarka, A., Rousarova, E., Capek, J., Rousar, T., Milovanovic, Z., Grujic-Milanovic, J., Jacevic, V., Kolla, J. N., Popr, M., Maurencova, D., Oleksak, P., Fresser, L., Kuca, K., Hodny, Z., & Nepovimova, E. (2026). In silico screening, synthesis, and biological evaluation of pyrazolopyrimidine-derived mTOR inhibitors for anticancer and senomorphic effects. Cancer Cell International. https://doi.org/10.1186/s12935-026-04308-0

Source records

crossref · retrieved 2026-09-26T13:51:49.562Z