Endothelial and neuronal engagement by AAV-BR1 gene therapy alleviates neurological symptoms and lipid deposition in a mouse model of Niemann-Pick type C2.
- DOI
- 10.1186/s12987-025-00621-4
- Published
- 2025 Jan 31
- Container
- Fluids and barriers of the CNS
- Publisher
- Not recorded
- Open access
- yes
Credibility signals
limited evidence Score 45/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.
Show all credibility signals
- cautionDOI registered: No matching Crossref record was present in this response.
- cautionDOI resolves: No matching Crossref record was present in this response.
- not scoredDirectory of Open Access Journals: No matching DOAJ record was present in this response. No allow-list match; this is not evidence of low credibility.
- not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made.
- not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made.
- not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made.
- not scoredROR affiliation: Not checked or no result supplied; no credibility inference made.
- not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete.
- not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete.
- not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete.
- not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete.
- supportingOpen access status: Normalized open-access status: open.
- not scoredPublication license: Not checked or no result supplied; no credibility inference made.
- not scoredPublication version: A publication version was supplied but is not scored.
- cautionMetadata completeness: 5 of 6 scored descriptive metadata groups are present; missing fields increase uncertainty.
Cite this work
BibTeX
@article{allodium:10.1186/s12987-025-00621-4,
title = {Endothelial and neuronal engagement by AAV-BR1 gene therapy alleviates neurological symptoms and lipid deposition in a mouse model of Niemann-Pick type C2.},
author = {Rasmussen CLM and Frederiksen SF and Heegaard CW and Thomsen MS and Hede E and Laczek B and Körbelin J and Wüstner D and Thomsen LB and Schwaninger M and Jensen ON and Moos T and Burkhart A},
year = {2025},
journal = {Fluids and barriers of the CNS},
doi = {10.1186/s12987-025-00621-4},
url = {https://doi.org/10.1186/s12987-025-00621-4}
}RIS
TY - JOUR TI - Endothelial and neuronal engagement by AAV-BR1 gene therapy alleviates neurological symptoms and lipid deposition in a mouse model of Niemann-Pick type C2. AU - Rasmussen CLM AU - Frederiksen SF AU - Heegaard CW AU - Thomsen MS AU - Hede E AU - Laczek B AU - Körbelin J AU - Wüstner D AU - Thomsen LB AU - Schwaninger M AU - Jensen ON AU - Moos T AU - Burkhart A PY - 2025 JO - Fluids and barriers of the CNS DO - 10.1186/s12987-025-00621-4 UR - https://doi.org/10.1186/s12987-025-00621-4 ER -
APA
CLM, R., SF, F., CW, H., MS, T., E, H., B, L., J, K., D, W., LB, T., M, S., ON, J., T, M., & A, B. (2025). Endothelial and neuronal engagement by AAV-BR1 gene therapy alleviates neurological symptoms and lipid deposition in a mouse model of Niemann-Pick type C2.. Fluids and barriers of the CNS. https://doi.org/10.1186/s12987-025-00621-4
Source records
- pubmed · retrieved 2026-09-25T21:30:53.921Z