Dual CAR-NK cells targeting PD-L1 and ErbB2 (HER2) exhibit cooperative CAR signaling and counteract solid tumor heterogeneity

Kristin Freudenberg-Jahn, Idan Ben-Horin, Nivedha Murali Shankar, Maria Schuldt, Paola Ortiz-Montero, Liliana R. Loureiro, Wiebke Rackwitz, Corinna Opitz, Lydia Krutz, Thomas Breither, Pranav Oberoi, Aline Häcker, Dirk Jäger, Jan Dominik Kuhlmann, Pauline Wimberger, Stephan R. Künzel, Kristina Hölig, Anja Feldmann, Michael Bachmann, Winfried S. Wels, Torsten Tonn, Jiri Eitler

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DOI: 10.1186/s13046-026-03722-6
Published: 2026-05-19
Container: Journal of Experimental & Clinical Cancer Research
Publisher: Springer Science and Business Media LLC
Open access: unknown

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Cite this work

BibTeX

@article{allodium:10.1186/s13046-026-03722-6,
  title = {Dual CAR-NK cells targeting PD-L1 and ErbB2 (HER2) exhibit cooperative CAR signaling and counteract solid tumor heterogeneity},
  author = {Kristin Freudenberg-Jahn and Idan Ben-Horin and Nivedha Murali Shankar and Maria Schuldt and Paola Ortiz-Montero and Liliana R. Loureiro and Wiebke Rackwitz and Corinna Opitz and Lydia Krutz and Thomas Breither and Pranav Oberoi and Aline Häcker and Dirk Jäger and Jan Dominik Kuhlmann and Pauline Wimberger and Stephan R. Künzel and Kristina Hölig and Anja Feldmann and Michael Bachmann and Winfried S. Wels and Torsten Tonn and Jiri Eitler},
  year = {2026},
  journal = {Journal of Experimental \&amp; Clinical Cancer Research},
  doi = {10.1186/s13046-026-03722-6},
  url = {https://doi.org/10.1186/s13046-026-03722-6}
}

RIS

TY  - JOUR
TI  - Dual CAR-NK cells targeting PD-L1 and ErbB2 (HER2) exhibit cooperative CAR signaling and counteract solid tumor heterogeneity
AU  - Kristin Freudenberg-Jahn
AU  - Idan Ben-Horin
AU  - Nivedha Murali Shankar
AU  - Maria Schuldt
AU  - Paola Ortiz-Montero
AU  - Liliana R. Loureiro
AU  - Wiebke Rackwitz
AU  - Corinna Opitz
AU  - Lydia Krutz
AU  - Thomas Breither
AU  - Pranav Oberoi
AU  - Aline Häcker
AU  - Dirk Jäger
AU  - Jan Dominik Kuhlmann
AU  - Pauline Wimberger
AU  - Stephan R. Künzel
AU  - Kristina Hölig
AU  - Anja Feldmann
AU  - Michael Bachmann
AU  - Winfried S. Wels
AU  - Torsten Tonn
AU  - Jiri Eitler
PY  - 2026
JO  - Journal of Experimental &amp; Clinical Cancer Research
DO  - 10.1186/s13046-026-03722-6
UR  - https://doi.org/10.1186/s13046-026-03722-6
ER  -

APA

Freudenberg-Jahn, K., Ben-Horin, I., Shankar, N. M., Schuldt, M., Ortiz-Montero, P., Loureiro, L. R., Rackwitz, W., Opitz, C., Krutz, L., Breither, T., Oberoi, P., Häcker, A., Jäger, D., Kuhlmann, J. D., Wimberger, P., Künzel, S. R., Hölig, K., Feldmann, A., Bachmann, M., Wels, W. S., Tonn, T., & Eitler, J. (2026). Dual CAR-NK cells targeting PD-L1 and ErbB2 (HER2) exhibit cooperative CAR signaling and counteract solid tumor heterogeneity. Journal of Experimental & Clinical Cancer Research. https://doi.org/10.1186/s13046-026-03722-6

Source records

crossref · retrieved 2026-09-26T10:38:07.559Z