A single-nucleus and spatial transcriptomic atlas of the COVID-19 liver reveals topological, functional, and regenerative organ disruption in patients.

Pita-Juarez Y, Karagkouni D, Kalavros N, Melms JC, Niezen S, Delorey TM, Essene AL, Brook OR, Pant D, Skelton-Badlani D, Naderi P, Huang P, Pan L, Hether T, Andrews TS, Ziegler CGK, Reeves J, Myloserdnyy A, Chen R, Nam A, Phelan S, Liang Y, Gregory M, He S, Patrick M, Rane T, Wardhani A, Amin AD, Biermann J, Hibshoosh H, Veregge M, Kramer Z, Jacobs C, Yalcin Y, Phillips D, Slyper M, Subramanian A, Ashenberg O, Bloom-Ackermann Z, Tran VM, Gomez J, Sturm A, Zhang S, Fleming SJ, Warren S, Beechem J, Hung D, Babadi M, Padera RF Jr, MacParland SA, Bader GD, Imad N, Solomon IH, Miller E, Riedel S, Porter CBM, Villani AC, Tsai LT, Hide W, Szabo G, Hecht J, Rozenblatt-Rosen O, Shalek AK, Izar B, Regev A, Popov YV, Jiang ZG, Vlachos IS

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DOI: 10.1186/s13059-025-03499-5
Published: 2025 Mar 14
Container: Genome biology
Publisher: Not recorded
Open access: yes

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Cite this work

BibTeX

@article{allodium:10.1186/s13059-025-03499-5,
  title = {A single-nucleus and spatial transcriptomic atlas of the COVID-19 liver reveals topological, functional, and regenerative organ disruption in patients.},
  author = {Pita-Juarez Y and Karagkouni D and Kalavros N and Melms JC and Niezen S and Delorey TM and Essene AL and Brook OR and Pant D and Skelton-Badlani D and Naderi P and Huang P and Pan L and Hether T and Andrews TS and Ziegler CGK and Reeves J and Myloserdnyy A and Chen R and Nam A and Phelan S and Liang Y and Gregory M and He S and Patrick M and Rane T and Wardhani A and Amin AD and Biermann J and Hibshoosh H and Veregge M and Kramer Z and Jacobs C and Yalcin Y and Phillips D and Slyper M and Subramanian A and Ashenberg O and Bloom-Ackermann Z and Tran VM and Gomez J and Sturm A and Zhang S and Fleming SJ and Warren S and Beechem J and Hung D and Babadi M and Padera RF Jr and MacParland SA and Bader GD and Imad N and Solomon IH and Miller E and Riedel S and Porter CBM and Villani AC and Tsai LT and Hide W and Szabo G and Hecht J and Rozenblatt-Rosen O and Shalek AK and Izar B and Regev A and Popov YV and Jiang ZG and Vlachos IS},
  year = {2025},
  journal = {Genome biology},
  doi = {10.1186/s13059-025-03499-5},
  url = {https://doi.org/10.1186/s13059-025-03499-5}
}

RIS

TY  - JOUR
TI  - A single-nucleus and spatial transcriptomic atlas of the COVID-19 liver reveals topological, functional, and regenerative organ disruption in patients.
AU  - Pita-Juarez Y
AU  - Karagkouni D
AU  - Kalavros N
AU  - Melms JC
AU  - Niezen S
AU  - Delorey TM
AU  - Essene AL
AU  - Brook OR
AU  - Pant D
AU  - Skelton-Badlani D
AU  - Naderi P
AU  - Huang P
AU  - Pan L
AU  - Hether T
AU  - Andrews TS
AU  - Ziegler CGK
AU  - Reeves J
AU  - Myloserdnyy A
AU  - Chen R
AU  - Nam A
AU  - Phelan S
AU  - Liang Y
AU  - Gregory M
AU  - He S
AU  - Patrick M
AU  - Rane T
AU  - Wardhani A
AU  - Amin AD
AU  - Biermann J
AU  - Hibshoosh H
AU  - Veregge M
AU  - Kramer Z
AU  - Jacobs C
AU  - Yalcin Y
AU  - Phillips D
AU  - Slyper M
AU  - Subramanian A
AU  - Ashenberg O
AU  - Bloom-Ackermann Z
AU  - Tran VM
AU  - Gomez J
AU  - Sturm A
AU  - Zhang S
AU  - Fleming SJ
AU  - Warren S
AU  - Beechem J
AU  - Hung D
AU  - Babadi M
AU  - Padera RF Jr
AU  - MacParland SA
AU  - Bader GD
AU  - Imad N
AU  - Solomon IH
AU  - Miller E
AU  - Riedel S
AU  - Porter CBM
AU  - Villani AC
AU  - Tsai LT
AU  - Hide W
AU  - Szabo G
AU  - Hecht J
AU  - Rozenblatt-Rosen O
AU  - Shalek AK
AU  - Izar B
AU  - Regev A
AU  - Popov YV
AU  - Jiang ZG
AU  - Vlachos IS
PY  - 2025
JO  - Genome biology
DO  - 10.1186/s13059-025-03499-5
UR  - https://doi.org/10.1186/s13059-025-03499-5
ER  -

APA

Y, P., D, K., N, K., JC, M., S, N., TM, D., AL, E., OR, B., D, P., D, S., P, N., P, H., L, P., T, H., TS, A., CGK, Z., J, R., A, M., R, C., A, N., S, P., Y, L., M, G., S, H., M, P., T, R., A, W., AD, A., J, B., H, H., M, V., Z, K., C, J., Y, Y., D, P., M, S., A, S., O, A., Z, B., VM, T., J, G., A, S., S, Z., SJ, F., S, W., J, B., D, H., M, B., Jr, P. R., SA, M., GD, B., N, I., IH, S., E, M., S, R., CBM, P., AC, V., LT, T., W, H., G, S., J, H., O, R., AK, S., B, I., A, R., YV, P., ZG, J., & IS, V. (2025). A single-nucleus and spatial transcriptomic atlas of the COVID-19 liver reveals topological, functional, and regenerative organ disruption in patients.. Genome biology. https://doi.org/10.1186/s13059-025-03499-5

Source records

pubmed · retrieved 2026-09-25T18:17:04.493Z