Type 2 diabetes risk alleles in peptidyl-glycine alpha-amidating monooxygenase influence GLP-1 levels and response to GLP-1 receptor agonists

Mahesh M. Umapathysivam, Elisa Araldi, Benoit Hastoy, Adem Y. Dawed, Hasan Vatandaslar, Johanna E. Mayrhofer, Peter Lindquist, Pamuditha N. Silva, Algera Goga, Geraldine O. Trüllinger, Svenja Godbersen, Shahana Sengupta, Adrian Kaufmann, Søren Krogsgaard Thomsen, Bolette Hartmann, Yi-Chun Chen, Anna E. Jonsson, Hasan Kabakci, Swaraj Thaman, Niels Grarup, Christian T. Have, Lindsay P. Pallo, Kristine Faerch, Anette P. Gjesing, Sameena Nawaz, Jane Cheeseman, Matthew J. Neville, Oluf Pedersen, Mark Walker, Han Sun, Christopher Jennison, Andrew T. Hattersley, Jens F. Rehfeld, Rury R. Holman, Bruce C. Verchere, Torben Hansen, Fredrik Karpe, Jens J. Holst, Mette M. Rosenkilde, Angus G. Jones, Michael Ristow, Mark I. McCarthy, Ewan R. Pearson, Markus Stoffel, Anna L. Gloyn

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DOI: 10.1186/s13073-026-01630-0
Published: 2026-03-29
Container: Genome Medicine
Publisher: Springer Science and Business Media LLC
Open access: unknown

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Cite this work

BibTeX

@article{allodium:10.1186/s13073-026-01630-0,
  title = {Type 2 diabetes risk alleles in peptidyl-glycine alpha-amidating monooxygenase influence GLP-1 levels and response to GLP-1 receptor agonists},
  author = {Mahesh M. Umapathysivam and Elisa Araldi and Benoit Hastoy and Adem Y. Dawed and Hasan Vatandaslar and Johanna E. Mayrhofer and Peter Lindquist and Pamuditha N. Silva and Algera Goga and Geraldine O. Trüllinger and Svenja Godbersen and Shahana Sengupta and Adrian Kaufmann and Søren Krogsgaard Thomsen and Bolette Hartmann and Yi-Chun Chen and Anna E. Jonsson and Hasan Kabakci and Swaraj Thaman and Niels Grarup and Christian T. Have and Lindsay P. Pallo and Kristine Faerch and Anette P. Gjesing and Sameena Nawaz and Jane Cheeseman and Matthew J. Neville and Oluf Pedersen and Mark Walker and Han Sun and Christopher Jennison and Andrew T. Hattersley and Jens F. Rehfeld and Rury R. Holman and Bruce C. Verchere and Torben Hansen and Fredrik Karpe and Jens J. Holst and Mette M. Rosenkilde and Angus G. Jones and Michael Ristow and Mark I. McCarthy and Ewan R. Pearson and Markus Stoffel and Anna L. Gloyn},
  year = {2026},
  journal = {Genome Medicine},
  doi = {10.1186/s13073-026-01630-0},
  url = {https://doi.org/10.1186/s13073-026-01630-0}
}

RIS

TY  - JOUR
TI  - Type 2 diabetes risk alleles in peptidyl-glycine alpha-amidating monooxygenase influence GLP-1 levels and response to GLP-1 receptor agonists
AU  - Mahesh M. Umapathysivam
AU  - Elisa Araldi
AU  - Benoit Hastoy
AU  - Adem Y. Dawed
AU  - Hasan Vatandaslar
AU  - Johanna E. Mayrhofer
AU  - Peter Lindquist
AU  - Pamuditha N. Silva
AU  - Algera Goga
AU  - Geraldine O. Trüllinger
AU  - Svenja Godbersen
AU  - Shahana Sengupta
AU  - Adrian Kaufmann
AU  - Søren Krogsgaard Thomsen
AU  - Bolette Hartmann
AU  - Yi-Chun Chen
AU  - Anna E. Jonsson
AU  - Hasan Kabakci
AU  - Swaraj Thaman
AU  - Niels Grarup
AU  - Christian T. Have
AU  - Lindsay P. Pallo
AU  - Kristine Faerch
AU  - Anette P. Gjesing
AU  - Sameena Nawaz
AU  - Jane Cheeseman
AU  - Matthew J. Neville
AU  - Oluf Pedersen
AU  - Mark Walker
AU  - Han Sun
AU  - Christopher Jennison
AU  - Andrew T. Hattersley
AU  - Jens F. Rehfeld
AU  - Rury R. Holman
AU  - Bruce C. Verchere
AU  - Torben Hansen
AU  - Fredrik Karpe
AU  - Jens J. Holst
AU  - Mette M. Rosenkilde
AU  - Angus G. Jones
AU  - Michael Ristow
AU  - Mark I. McCarthy
AU  - Ewan R. Pearson
AU  - Markus Stoffel
AU  - Anna L. Gloyn
PY  - 2026
JO  - Genome Medicine
DO  - 10.1186/s13073-026-01630-0
UR  - https://doi.org/10.1186/s13073-026-01630-0
ER  -

APA

Umapathysivam, M. M., Araldi, E., Hastoy, B., Dawed, A. Y., Vatandaslar, H., Mayrhofer, J. E., Lindquist, P., Silva, P. N., Goga, A., Trüllinger, G. O., Godbersen, S., Sengupta, S., Kaufmann, A., Thomsen, S. K., Hartmann, B., Chen, Y., Jonsson, A. E., Kabakci, H., Thaman, S., Grarup, N., Have, C. T., Pallo, L. P., Faerch, K., Gjesing, A. P., Nawaz, S., Cheeseman, J., Neville, M. J., Pedersen, O., Walker, M., Sun, H., Jennison, C., Hattersley, A. T., Rehfeld, J. F., Holman, R. R., Verchere, B. C., Hansen, T., Karpe, F., Holst, J. J., Rosenkilde, M. M., Jones, A. G., Ristow, M., McCarthy, M. I., Pearson, E. R., Stoffel, M., & Gloyn, A. L. (2026). Type 2 diabetes risk alleles in peptidyl-glycine alpha-amidating monooxygenase influence GLP-1 levels and response to GLP-1 receptor agonists. Genome Medicine. https://doi.org/10.1186/s13073-026-01630-0

Source records

crossref · retrieved 2026-09-26T14:12:38.313Z