ESR1 mutations and CDK4/6 inhibitor choice shape clonal selection and adaptive cell states during acquired resistance

Cristina Guarducci, Daniel Abravanel, Douglas Russo, Kavya Prasad, Jingxin Fu, Zsuzsanna Nagy, Vishwajit Rao, Agostina Nardone, Yanan Kuang, Avery Feit, Wen Ma, Gabriella Cohen Feit, Francisco Hermida-Prado, Capucine Heraud, Miguel Munoz Gomez, Diana Elisa Garcia Cortes, Patrick Kurnia, Jorge Gomez Tejeda Zanudo, Rong Li, Xintao Qiu, Simona Cristea, Ariel Feiglin, Yu-Chen Cheng, Nancy U. Lin, Sara M. Tolaney, Luca Malorni, Piotr Sicinski, Kornelia Polyak, Cloud Paweletz, Henry Long, Chip Stewart, Franziska Michor, Gad Getz, Myles Brown, Rinath Jeselsohn

Open source

DOI: 10.1186/s13073-026-01690-2
Published: 2026-06-27
Container: Genome Medicine
Publisher: Springer Science and Business Media LLC
Open access: unknown

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Cite this work

BibTeX

@article{allodium:10.1186/s13073-026-01690-2,
  title = {ESR1 mutations and CDK4/6 inhibitor choice shape clonal selection and adaptive cell states during acquired resistance},
  author = {Cristina Guarducci and Daniel Abravanel and Douglas Russo and Kavya Prasad and Jingxin Fu and Zsuzsanna Nagy and Vishwajit Rao and Agostina Nardone and Yanan Kuang and Avery Feit and Wen Ma and Gabriella Cohen Feit and Francisco Hermida-Prado and Capucine Heraud and Miguel Munoz Gomez and Diana Elisa Garcia Cortes and Patrick Kurnia and Jorge Gomez Tejeda Zanudo and Rong Li and Xintao Qiu and Simona Cristea and Ariel Feiglin and Yu-Chen Cheng and Nancy U. Lin and Sara M. Tolaney and Luca Malorni and Piotr Sicinski and Kornelia Polyak and Cloud Paweletz and Henry Long and Chip Stewart and Franziska Michor and Gad Getz and Myles Brown and Rinath Jeselsohn},
  year = {2026},
  journal = {Genome Medicine},
  doi = {10.1186/s13073-026-01690-2},
  url = {https://doi.org/10.1186/s13073-026-01690-2}
}

RIS

TY  - JOUR
TI  - ESR1 mutations and CDK4/6 inhibitor choice shape clonal selection and adaptive cell states during acquired resistance
AU  - Cristina Guarducci
AU  - Daniel Abravanel
AU  - Douglas Russo
AU  - Kavya Prasad
AU  - Jingxin Fu
AU  - Zsuzsanna Nagy
AU  - Vishwajit Rao
AU  - Agostina Nardone
AU  - Yanan Kuang
AU  - Avery Feit
AU  - Wen Ma
AU  - Gabriella Cohen Feit
AU  - Francisco Hermida-Prado
AU  - Capucine Heraud
AU  - Miguel Munoz Gomez
AU  - Diana Elisa Garcia Cortes
AU  - Patrick Kurnia
AU  - Jorge Gomez Tejeda Zanudo
AU  - Rong Li
AU  - Xintao Qiu
AU  - Simona Cristea
AU  - Ariel Feiglin
AU  - Yu-Chen Cheng
AU  - Nancy U. Lin
AU  - Sara M. Tolaney
AU  - Luca Malorni
AU  - Piotr Sicinski
AU  - Kornelia Polyak
AU  - Cloud Paweletz
AU  - Henry Long
AU  - Chip Stewart
AU  - Franziska Michor
AU  - Gad Getz
AU  - Myles Brown
AU  - Rinath Jeselsohn
PY  - 2026
JO  - Genome Medicine
DO  - 10.1186/s13073-026-01690-2
UR  - https://doi.org/10.1186/s13073-026-01690-2
ER  -

APA

Guarducci, C., Abravanel, D., Russo, D., Prasad, K., Fu, J., Nagy, Z., Rao, V., Nardone, A., Kuang, Y., Feit, A., Ma, W., Feit, G. C., Hermida-Prado, F., Heraud, C., Gomez, M. M., Cortes, D. E. G., Kurnia, P., Zanudo, J. G. T., Li, R., Qiu, X., Cristea, S., Feiglin, A., Cheng, Y., Lin, N. U., Tolaney, S. M., Malorni, L., Sicinski, P., Polyak, K., Paweletz, C., Long, H., Stewart, C., Michor, F., Getz, G., Brown, M., & Jeselsohn, R. (2026). ESR1 mutations and CDK4/6 inhibitor choice shape clonal selection and adaptive cell states during acquired resistance. Genome Medicine. https://doi.org/10.1186/s13073-026-01690-2

Source records

crossref · retrieved 2026-11-06T10:52:10.463Z