The 12 o’clock assay: an optimized dodecaplex droplet digital PCR assay for robust DNA methylation quantification and epigenetic clock-based age-predictions

Ilef Hchaichi, Imène Garali, Alina-Madalina Popa, Antoine Daunay, Nicolas P. Tessier, Mourad Sahbatou, Lise M. Hardy, Aurore Rampanou, Hélène Blanché, Jean-François Zagury, Mathilde Touvier, Hélène Le Buanec, Shufang Renault, Nicolas Girerd, Jean-François Deleuze, Alexandre How-Kit

Open source

DOI
10.1186/s13148-026-02105-0
Published
2026-03-24
Container
Clinical Epigenetics
Publisher
Springer Science and Business Media LLC
Open access
unknown

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BibTeX

@article{allodium:10.1186/s13148-026-02105-0,
  title = {The 12 o’clock assay: an optimized dodecaplex droplet digital PCR assay for robust DNA methylation quantification and epigenetic clock-based age-predictions},
  author = {Ilef Hchaichi and Imène Garali and Alina-Madalina Popa and Antoine Daunay and Nicolas P. Tessier and Mourad Sahbatou and Lise M. Hardy and Aurore Rampanou and Hélène Blanché and Jean-François Zagury and Mathilde Touvier and Hélène Le Buanec and Shufang Renault and Nicolas Girerd and Jean-François Deleuze and Alexandre How-Kit},
  year = {2026},
  journal = {Clinical Epigenetics},
  doi = {10.1186/s13148-026-02105-0},
  url = {https://doi.org/10.1186/s13148-026-02105-0}
}

RIS

TY  - JOUR
TI  - The 12 o’clock assay: an optimized dodecaplex droplet digital PCR assay for robust DNA methylation quantification and epigenetic clock-based age-predictions
AU  - Ilef Hchaichi
AU  - Imène Garali
AU  - Alina-Madalina Popa
AU  - Antoine Daunay
AU  - Nicolas P. Tessier
AU  - Mourad Sahbatou
AU  - Lise M. Hardy
AU  - Aurore Rampanou
AU  - Hélène Blanché
AU  - Jean-François Zagury
AU  - Mathilde Touvier
AU  - Hélène Le Buanec
AU  - Shufang Renault
AU  - Nicolas Girerd
AU  - Jean-François Deleuze
AU  - Alexandre How-Kit
PY  - 2026
JO  - Clinical Epigenetics
DO  - 10.1186/s13148-026-02105-0
UR  - https://doi.org/10.1186/s13148-026-02105-0
ER  - 

APA

Hchaichi, I., Garali, I., Popa, A., Daunay, A., Tessier, N. P., Sahbatou, M., Hardy, L. M., Rampanou, A., Blanché, H., Zagury, J., Touvier, M., Buanec, H. L., Renault, S., Girerd, N., Deleuze, J., & How-Kit, A. (2026). The 12 o’clock assay: an optimized dodecaplex droplet digital PCR assay for robust DNA methylation quantification and epigenetic clock-based age-predictions. Clinical Epigenetics. https://doi.org/10.1186/s13148-026-02105-0

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