[(18)F]MNI-1054, a novel PET ligand for lysine-specific histone demethylase 1 A (LSD1): first-in human validation and enzyme occupancy of the LSD1 inhibitor TAK-418.

Schwarz AJ, Sandiego CM, Constantinescu C, Takano A, McQuade P, Tauscher J, Daegele N, Marek K, Gunn RN, Madonia J, Russell DS

Open source

DOI
10.1186/s13550-026-01477-x
Published
2026 Jul 3
Container
EJNMMI research
Publisher
Not recorded
Open access
yes

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BibTeX

@article{allodium:10.1186/s13550-026-01477-x,
  title = {[(18)F]MNI-1054, a novel PET ligand for lysine-specific histone demethylase 1 A (LSD1): first-in human validation and enzyme occupancy of the LSD1 inhibitor TAK-418.},
  author = {Schwarz AJ and Sandiego CM and Constantinescu C and Takano A and McQuade P and Tauscher J and Daegele N and Marek K and Gunn RN and Madonia J and Russell DS},
  year = {2026},
  journal = {EJNMMI research},
  doi = {10.1186/s13550-026-01477-x},
  url = {https://doi.org/10.1186/s13550-026-01477-x}
}

RIS

TY  - JOUR
TI  - [(18)F]MNI-1054, a novel PET ligand for lysine-specific histone demethylase 1 A (LSD1): first-in human validation and enzyme occupancy of the LSD1 inhibitor TAK-418.
AU  - Schwarz AJ
AU  - Sandiego CM
AU  - Constantinescu C
AU  - Takano A
AU  - McQuade P
AU  - Tauscher J
AU  - Daegele N
AU  - Marek K
AU  - Gunn RN
AU  - Madonia J
AU  - Russell DS
PY  - 2026
JO  - EJNMMI research
DO  - 10.1186/s13550-026-01477-x
UR  - https://doi.org/10.1186/s13550-026-01477-x
ER  - 

APA

AJ, S., CM, S., C, C., A, T., P, M., J, T., N, D., K, M., RN, G., J, M., & DS, R. (2026). [(18)F]MNI-1054, a novel PET ligand for lysine-specific histone demethylase 1 A (LSD1): first-in human validation and enzyme occupancy of the LSD1 inhibitor TAK-418.. EJNMMI research. https://doi.org/10.1186/s13550-026-01477-x

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