Impact of Zinc Supplementation and Topical Clobetasol on the Prevention of Regorafenib-Induced Hand-Foot Skin Reaction: The ZINCLO-HAND Study

Orhun Akdogan, Enes Yesilbas, Mesut Yılmaz, Fatma Keskin Uzundere, Ahmet Oruc, Ender Eren Ozcelik, Gorkem Turhan, Mehmet Kayaalp, Ilknur Deliktas Onur, Haydar Temizyurek, Yasemin Evlendi, Okan Avcı, Mahmut Kara, Galip Can Uyar, Hasibe Bilge Gür, Ugur Coskun, Kadriye Baskurt, Fatma Cetin, Aytug Uner, Ramazan Cosar, Cengiz Karacin, Gungor Utkan, Atila Yıldırım, Ahmet Bilgehan Sahin, Ahmet Ozet, Mehmet Artac, Muhammed Ali Kaplan, Kadriye Bir Yucel, Nuriye Ozdemir, Omer Dizdar, Ozan Yazıcı, Osman Sutcuoglu

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DOI: 10.1200/op-26-00226
Published: 2026-11-04
Container: JCO Oncology Practice
Publisher: American Society of Clinical Oncology (ASCO)
Open access: unknown

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Cite this work

BibTeX

@article{allodium:10.1200/op-26-00226,
  title = {Impact of Zinc Supplementation and Topical Clobetasol on the Prevention of Regorafenib-Induced Hand-Foot Skin Reaction: The ZINCLO-HAND Study},
  author = {Orhun Akdogan and Enes Yesilbas and Mesut Yılmaz and Fatma Keskin Uzundere and Ahmet Oruc and Ender Eren Ozcelik and Gorkem Turhan and Mehmet Kayaalp and Ilknur Deliktas Onur and Haydar Temizyurek and Yasemin Evlendi and Okan Avcı and Mahmut Kara and Galip Can Uyar and Hasibe Bilge Gür and Ugur Coskun and Kadriye Baskurt and Fatma Cetin and Aytug Uner and Ramazan Cosar and Cengiz Karacin and Gungor Utkan and Atila Yıldırım and Ahmet Bilgehan Sahin and Ahmet Ozet and Mehmet Artac and Muhammed Ali Kaplan and Kadriye Bir Yucel and Nuriye Ozdemir and Omer Dizdar and Ozan Yazıcı and Osman Sutcuoglu},
  year = {2026},
  journal = {JCO Oncology Practice},
  doi = {10.1200/op-26-00226},
  url = {https://doi.org/10.1200/op-26-00226}
}

RIS

TY  - JOUR
TI  - Impact of Zinc Supplementation and Topical Clobetasol on the Prevention of Regorafenib-Induced Hand-Foot Skin Reaction: The ZINCLO-HAND Study
AU  - Orhun Akdogan
AU  - Enes Yesilbas
AU  - Mesut Yılmaz
AU  - Fatma Keskin Uzundere
AU  - Ahmet Oruc
AU  - Ender Eren Ozcelik
AU  - Gorkem Turhan
AU  - Mehmet Kayaalp
AU  - Ilknur Deliktas Onur
AU  - Haydar Temizyurek
AU  - Yasemin Evlendi
AU  - Okan Avcı
AU  - Mahmut Kara
AU  - Galip Can Uyar
AU  - Hasibe Bilge Gür
AU  - Ugur Coskun
AU  - Kadriye Baskurt
AU  - Fatma Cetin
AU  - Aytug Uner
AU  - Ramazan Cosar
AU  - Cengiz Karacin
AU  - Gungor Utkan
AU  - Atila Yıldırım
AU  - Ahmet Bilgehan Sahin
AU  - Ahmet Ozet
AU  - Mehmet Artac
AU  - Muhammed Ali Kaplan
AU  - Kadriye Bir Yucel
AU  - Nuriye Ozdemir
AU  - Omer Dizdar
AU  - Ozan Yazıcı
AU  - Osman Sutcuoglu
PY  - 2026
JO  - JCO Oncology Practice
DO  - 10.1200/op-26-00226
UR  - https://doi.org/10.1200/op-26-00226
ER  -

APA

Akdogan, O., Yesilbas, E., Yılmaz, M., Uzundere, F. K., Oruc, A., Ozcelik, E. E., Turhan, G., Kayaalp, M., Onur, I. D., Temizyurek, H., Evlendi, Y., Avcı, O., Kara, M., Uyar, G. C., Gür, H. B., Coskun, U., Baskurt, K., Cetin, F., Uner, A., Cosar, R., Karacin, C., Utkan, G., Yıldırım, A., Sahin, A. B., Ozet, A., Artac, M., Kaplan, M. A., Yucel, K. B., Ozdemir, N., Dizdar, O., Yazıcı, O., & Sutcuoglu, O. (2026). Impact of Zinc Supplementation and Topical Clobetasol on the Prevention of Regorafenib-Induced Hand-Foot Skin Reaction: The ZINCLO-HAND Study. JCO Oncology Practice. https://doi.org/10.1200/op-26-00226

Source records

crossref · retrieved 2026-11-06T08:52:25.872Z