EOAD-Signature Atrophy Predicts Dementia in Early-Onset MCI due to Alzheimer Disease

Thiago Paranhos, Yuta Katsumi, Michael Joseph Brickhouse, Ani Eloyan, Ryan Eckbo, Alexander Zaitsev, Anna Du, Renaud La Joie, Maryanne Thangarajah, Alexander Taurone, Prashanthi Vemuri, Clifford R. Jack, Unknown, Dustin B. Hammers, Paul S. Aisen, Laurel A. Beckett, Robert Koeppe, Walter A. Kukull, Arthur W. Toga, Alireza Atri, David Glenn Clark, Gregory S. Day, Ranjan Duara, Neill R. Graff-Radford, Ian M. Grant, Lawrence S. Honig, Erik Johnson, David T. Jones, Joseph C. Masdeu, Mario F. Mendez, Erik S. Musiek, Chiadi U. Onyike, Meghan Riddle, Emily Rogalski, Stephen Salloway, Sharon J. Sha, Raymond Scott Turner, Thomas Wingo, David A. Wolk, Kyle B. Womack, Maria C. Carrillo, Gil Dan Rabinovici, Liana G. Apostolova, Bradford Clark Dickerson, Mark C. Eldaief, Alexandra Touroutoglou

Open source

DOI: 10.1212/wnl.0000000000218519
Published: 2026-10-13
Container: Neurology
Publisher: Ovid Technologies (Wolters Kluwer Health)
Open access: unknown

Credibility signals

uncertain Score 64/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

supportingDOI registered: A matching record was returned by Crossref. Source: Crossref; license: CC0 metadata
supportingDOI resolves: A matching record was returned by Crossref. Source: Crossref; license: CC0 metadata
not scoredDirectory of Open Access Journals: No matching DOAJ record was present in this response. No allow-list match; this is not evidence of low credibility. Source: DOAJ; license: CC0
not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredROR affiliation: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredOpen access status: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication license: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication version: A publication version was supplied but is not scored. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
supportingMetadata completeness: All 6 scored descriptive metadata groups are present. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

Cite this work

BibTeX

@article{allodium:10.1212/wnl.0000000000218519,
  title = {EOAD-Signature Atrophy Predicts Dementia in Early-Onset MCI due to Alzheimer Disease},
  author = {Thiago Paranhos and Yuta Katsumi and Michael Joseph Brickhouse and Ani Eloyan and Ryan Eckbo and Alexander Zaitsev and Anna Du and Renaud La Joie and Maryanne Thangarajah and Alexander Taurone and Prashanthi Vemuri and Clifford R. Jack and Unknown and Dustin B. Hammers and Paul S. Aisen and Laurel A. Beckett and Robert Koeppe and Walter A. Kukull and Arthur W. Toga and Alireza Atri and David Glenn Clark and Gregory S. Day and Ranjan Duara and Neill R. Graff-Radford and Ian M. Grant and Lawrence S. Honig and Erik Johnson and David T. Jones and Joseph C. Masdeu and Mario F. Mendez and Erik S. Musiek and Chiadi U. Onyike and Meghan Riddle and Emily Rogalski and Stephen Salloway and Sharon J. Sha and Raymond Scott Turner and Thomas Wingo and David A. Wolk and Kyle B. Womack and Maria C. Carrillo and Gil Dan Rabinovici and Liana G. Apostolova and Bradford Clark Dickerson and Mark C. Eldaief and Alexandra Touroutoglou},
  year = {2026},
  journal = {Neurology},
  doi = {10.1212/wnl.0000000000218519},
  url = {https://doi.org/10.1212/wnl.0000000000218519}
}

RIS

TY  - JOUR
TI  - EOAD-Signature Atrophy Predicts Dementia in Early-Onset MCI due to Alzheimer Disease
AU  - Thiago Paranhos
AU  - Yuta Katsumi
AU  - Michael Joseph Brickhouse
AU  - Ani Eloyan
AU  - Ryan Eckbo
AU  - Alexander Zaitsev
AU  - Anna Du
AU  - Renaud La Joie
AU  - Maryanne Thangarajah
AU  - Alexander Taurone
AU  - Prashanthi Vemuri
AU  - Clifford R. Jack
AU  - Unknown
AU  - Dustin B. Hammers
AU  - Paul S. Aisen
AU  - Laurel A. Beckett
AU  - Robert Koeppe
AU  - Walter A. Kukull
AU  - Arthur W. Toga
AU  - Alireza Atri
AU  - David Glenn Clark
AU  - Gregory S. Day
AU  - Ranjan Duara
AU  - Neill R. Graff-Radford
AU  - Ian M. Grant
AU  - Lawrence S. Honig
AU  - Erik Johnson
AU  - David T. Jones
AU  - Joseph C. Masdeu
AU  - Mario F. Mendez
AU  - Erik S. Musiek
AU  - Chiadi U. Onyike
AU  - Meghan Riddle
AU  - Emily Rogalski
AU  - Stephen Salloway
AU  - Sharon J. Sha
AU  - Raymond Scott Turner
AU  - Thomas Wingo
AU  - David A. Wolk
AU  - Kyle B. Womack
AU  - Maria C. Carrillo
AU  - Gil Dan Rabinovici
AU  - Liana G. Apostolova
AU  - Bradford Clark Dickerson
AU  - Mark C. Eldaief
AU  - Alexandra Touroutoglou
PY  - 2026
JO  - Neurology
DO  - 10.1212/wnl.0000000000218519
UR  - https://doi.org/10.1212/wnl.0000000000218519
ER  -

APA

Paranhos, T., Katsumi, Y., Brickhouse, M. J., Eloyan, A., Eckbo, R., Zaitsev, A., Du, A., Joie, R. L., Thangarajah, M., Taurone, A., Vemuri, P., Jack, C. R., Unknown, Hammers, D. B., Aisen, P. S., Beckett, L. A., Koeppe, R., Kukull, W. A., Toga, A. W., Atri, A., Clark, D. G., Day, G. S., Duara, R., Graff-Radford, N. R., Grant, I. M., Honig, L. S., Johnson, E., Jones, D. T., Masdeu, J. C., Mendez, M. F., Musiek, E. S., Onyike, C. U., Riddle, M., Rogalski, E., Salloway, S., Sha, S. J., Turner, R. S., Wingo, T., Wolk, D. A., Womack, K. B., Carrillo, M. C., Rabinovici, G. D., Apostolova, L. G., Dickerson, B. C., Eldaief, M. C., & Touroutoglou, A. (2026). EOAD-Signature Atrophy Predicts Dementia in Early-Onset MCI due to Alzheimer Disease. Neurology. https://doi.org/10.1212/wnl.0000000000218519

Source records

crossref · retrieved 2026-09-26T09:31:09.655Z