Isoflurane activates the type 1 ryanodine receptor to induce anesthesia in mice

Hiroyuki J. Kanaya, Ken Kuwajima, Yuko Ito, Yuta Shinohara, Yohei Okubo, Shinnosuke Shiono, Fumiya Tatsuki, Rei-ichiro Ohno, Hideki Ukai, Maki Ukai-Tadenuma, Kenta Sumiyama, Hiroshi Fujishima, Rikuhiro G. Yamada, Daisuke Tone, Hiroshi Kiyonari, Masaki Kikuchi, Takashi Umehara, Takashi Murayama, Kazunori Kanemaru, Masamitsu Iino, Koji L. Ode, Takatsugu Hirokawa, Hiroki R. Ueda

Open source

DOI: 10.1371/journal.pbio.3003172
Published: 2025-06-03
Container: PLOS Biology
Publisher: Public Library of Science (PLoS)
Open access: unknown

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Cite this work

BibTeX

@article{allodium:10.1371/journal.pbio.3003172,
  title = {Isoflurane activates the type 1 ryanodine receptor to induce anesthesia in mice},
  author = {Hiroyuki J. Kanaya and Ken Kuwajima and Yuko Ito and Yuta Shinohara and Yohei Okubo and Shinnosuke Shiono and Fumiya Tatsuki and Rei-ichiro Ohno and Hideki Ukai and Maki Ukai-Tadenuma and Kenta Sumiyama and Hiroshi Fujishima and Rikuhiro G. Yamada and Daisuke Tone and Hiroshi Kiyonari and Masaki Kikuchi and Takashi Umehara and Takashi Murayama and Kazunori Kanemaru and Masamitsu Iino and Koji L. Ode and Takatsugu Hirokawa and Hiroki R. Ueda},
  year = {2025},
  journal = {PLOS Biology},
  doi = {10.1371/journal.pbio.3003172},
  url = {https://doi.org/10.1371/journal.pbio.3003172}
}

RIS

TY  - JOUR
TI  - Isoflurane activates the type 1 ryanodine receptor to induce anesthesia in mice
AU  - Hiroyuki J. Kanaya
AU  - Ken Kuwajima
AU  - Yuko Ito
AU  - Yuta Shinohara
AU  - Yohei Okubo
AU  - Shinnosuke Shiono
AU  - Fumiya Tatsuki
AU  - Rei-ichiro Ohno
AU  - Hideki Ukai
AU  - Maki Ukai-Tadenuma
AU  - Kenta Sumiyama
AU  - Hiroshi Fujishima
AU  - Rikuhiro G. Yamada
AU  - Daisuke Tone
AU  - Hiroshi Kiyonari
AU  - Masaki Kikuchi
AU  - Takashi Umehara
AU  - Takashi Murayama
AU  - Kazunori Kanemaru
AU  - Masamitsu Iino
AU  - Koji L. Ode
AU  - Takatsugu Hirokawa
AU  - Hiroki R. Ueda
PY  - 2025
JO  - PLOS Biology
DO  - 10.1371/journal.pbio.3003172
UR  - https://doi.org/10.1371/journal.pbio.3003172
ER  -

APA

Kanaya, H. J., Kuwajima, K., Ito, Y., Shinohara, Y., Okubo, Y., Shiono, S., Tatsuki, F., Ohno, R., Ukai, H., Ukai-Tadenuma, M., Sumiyama, K., Fujishima, H., Yamada, R. G., Tone, D., Kiyonari, H., Kikuchi, M., Umehara, T., Murayama, T., Kanemaru, K., Iino, M., Ode, K. L., Hirokawa, T., & Ueda, H. R. (2025). Isoflurane activates the type 1 ryanodine receptor to induce anesthesia in mice. PLOS Biology. https://doi.org/10.1371/journal.pbio.3003172

Source records

crossref · retrieved 2026-09-25T10:32:54.287Z