Derepression of the epithelial transcription factor GRHL2 promotes direct hepatocyte-to-cholangiocyte transdifferentiation

Ludivine Vasseur, Céline Gheeraert, Julie Dubois-Chevalier, Ninon Very, Loïc Guille, Mohamed Bou Saleh, Clémence Boulet, Cyril Sobolewski, Pascal Loyer, Alexandre Berthier, Noémie Legrand, Anne Corlu, Viviane Gnemmi, Guillaume Lasailly, Emmanuelle Leteurtre, Dmitry Galinousky, Antonino Bongiovanni, Solenne Taront, Nicolaj I. Toft, Lars Grøntved, David Tulasne, Alessandro Furlan, Line Carolle Ntandja-Wandji, Bart Staels, Philippe Lefebvre, Laurent Dubuquoy, Jérôme Eeckhoute

Open source

DOI: 10.1371/journal.pbio.3003547
Published: 2025-12-12
Container: PLOS Biology
Publisher: Public Library of Science (PLoS)
Open access: unknown

Credibility signals

uncertain Score 64/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

supportingDOI registered: A matching record was returned by Crossref. Source: Crossref; license: CC0 metadata
supportingDOI resolves: A matching record was returned by Crossref. Source: Crossref; license: CC0 metadata
not scoredDirectory of Open Access Journals: No matching DOAJ record was present in this response. No allow-list match; this is not evidence of low credibility. Source: DOAJ; license: CC0
not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredROR affiliation: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredOpen access status: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication license: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication version: A publication version was supplied but is not scored. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
supportingMetadata completeness: All 6 scored descriptive metadata groups are present. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

Cite this work

BibTeX

@article{allodium:10.1371/journal.pbio.3003547,
  title = {Derepression of the epithelial transcription factor GRHL2 promotes direct hepatocyte-to-cholangiocyte transdifferentiation},
  author = {Ludivine Vasseur and Céline Gheeraert and Julie Dubois-Chevalier and Ninon Very and Loïc Guille and Mohamed Bou Saleh and Clémence Boulet and Cyril Sobolewski and Pascal Loyer and Alexandre Berthier and Noémie Legrand and Anne Corlu and Viviane Gnemmi and Guillaume Lasailly and Emmanuelle Leteurtre and Dmitry Galinousky and Antonino Bongiovanni and Solenne Taront and Nicolaj I. Toft and Lars Grøntved and David Tulasne and Alessandro Furlan and Line Carolle Ntandja-Wandji and Bart Staels and Philippe Lefebvre and Laurent Dubuquoy and Jérôme Eeckhoute},
  year = {2025},
  journal = {PLOS Biology},
  doi = {10.1371/journal.pbio.3003547},
  url = {https://doi.org/10.1371/journal.pbio.3003547}
}

RIS

TY  - JOUR
TI  - Derepression of the epithelial transcription factor GRHL2 promotes direct hepatocyte-to-cholangiocyte transdifferentiation
AU  - Ludivine Vasseur
AU  - Céline Gheeraert
AU  - Julie Dubois-Chevalier
AU  - Ninon Very
AU  - Loïc Guille
AU  - Mohamed Bou Saleh
AU  - Clémence Boulet
AU  - Cyril Sobolewski
AU  - Pascal Loyer
AU  - Alexandre Berthier
AU  - Noémie Legrand
AU  - Anne Corlu
AU  - Viviane Gnemmi
AU  - Guillaume Lasailly
AU  - Emmanuelle Leteurtre
AU  - Dmitry Galinousky
AU  - Antonino Bongiovanni
AU  - Solenne Taront
AU  - Nicolaj I. Toft
AU  - Lars Grøntved
AU  - David Tulasne
AU  - Alessandro Furlan
AU  - Line Carolle Ntandja-Wandji
AU  - Bart Staels
AU  - Philippe Lefebvre
AU  - Laurent Dubuquoy
AU  - Jérôme Eeckhoute
PY  - 2025
JO  - PLOS Biology
DO  - 10.1371/journal.pbio.3003547
UR  - https://doi.org/10.1371/journal.pbio.3003547
ER  -

APA

Vasseur, L., Gheeraert, C., Dubois-Chevalier, J., Very, N., Guille, L., Saleh, M. B., Boulet, C., Sobolewski, C., Loyer, P., Berthier, A., Legrand, N., Corlu, A., Gnemmi, V., Lasailly, G., Leteurtre, E., Galinousky, D., Bongiovanni, A., Taront, S., Toft, N. I., Grøntved, L., Tulasne, D., Furlan, A., Ntandja-Wandji, L. C., Staels, B., Lefebvre, P., Dubuquoy, L., & Eeckhoute, J. (2025). Derepression of the epithelial transcription factor GRHL2 promotes direct hepatocyte-to-cholangiocyte transdifferentiation. PLOS Biology. https://doi.org/10.1371/journal.pbio.3003547

Source records

crossref · retrieved 2026-09-27T12:37:29.588Z