Supporting clinical guidelines for opioid conversion to methadone and tapering to prevent withdrawal in critically ill children using physiology based pharmacokinetic modeling and simulation

Marika A. de Hoop-Sommen, Sahar Alozai, Violette M. G. J. Gijsen, Tjitske M. van der Zanden, Henry T. Akinbi, Tomoyuki Mizuno, Alexander A. Vinks, Rick Greupink, Saskia N. de Wildt

Open source

DOI
10.1371/journal.pone.0356917
Published
2026-09-08
Container
PLOS One
Publisher
Public Library of Science (PLoS)
Open access
unknown

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BibTeX

@article{allodium:10.1371/journal.pone.0356917,
  title = {Supporting clinical guidelines for opioid conversion to methadone and tapering to prevent withdrawal in critically ill children using physiology based pharmacokinetic modeling and simulation},
  author = {Marika A. de Hoop-Sommen and Sahar Alozai and Violette M. G. J. Gijsen and Tjitske M. van der Zanden and Henry T. Akinbi and Tomoyuki Mizuno and Alexander A. Vinks and Rick Greupink and Saskia N. de Wildt},
  year = {2026},
  journal = {PLOS One},
  doi = {10.1371/journal.pone.0356917},
  url = {https://doi.org/10.1371/journal.pone.0356917}
}

RIS

TY  - JOUR
TI  - Supporting clinical guidelines for opioid conversion to methadone and tapering to prevent withdrawal in critically ill children using physiology based pharmacokinetic modeling and simulation
AU  - Marika A. de Hoop-Sommen
AU  - Sahar Alozai
AU  - Violette M. G. J. Gijsen
AU  - Tjitske M. van der Zanden
AU  - Henry T. Akinbi
AU  - Tomoyuki Mizuno
AU  - Alexander A. Vinks
AU  - Rick Greupink
AU  - Saskia N. de Wildt
PY  - 2026
JO  - PLOS One
DO  - 10.1371/journal.pone.0356917
UR  - https://doi.org/10.1371/journal.pone.0356917
ER  - 

APA

Hoop-Sommen, M. A. D., Alozai, S., Gijsen, V. M. G. J., Zanden, T. M. V. D., Akinbi, H. T., Mizuno, T., Vinks, A. A., Greupink, R., & Wildt, S. N. D. (2026). Supporting clinical guidelines for opioid conversion to methadone and tapering to prevent withdrawal in critically ill children using physiology based pharmacokinetic modeling and simulation. PLOS One. https://doi.org/10.1371/journal.pone.0356917

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