Unveiling the neuroinflammatory potential of aspartame in Alzheimer’s disease: A comprehensive network toxicology and experimental validation approach

Dongyang Li, Xuejun Weng, Yijuan Huang, Dongni Yang, Shunhan Yao, Weihao Zheng, Xiaohong Jiang, Yilin Wei, Sheng Xu, Chunwei Wei

Open source

DOI: 10.1371/journal.pone.0361766
Published: 2026-11-03
Container: PLOS One
Publisher: Public Library of Science (PLoS)
Open access: unknown

Credibility signals

uncertain Score 64/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

supportingDOI registered: A matching record was returned by Crossref. Source: Crossref; license: CC0 metadata
supportingDOI resolves: A matching record was returned by Crossref. Source: Crossref; license: CC0 metadata
not scoredDirectory of Open Access Journals: No matching DOAJ record was present in this response. No allow-list match; this is not evidence of low credibility. Source: DOAJ; license: CC0
not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredROR affiliation: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredOpen access status: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication license: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication version: A publication version was supplied but is not scored. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
supportingMetadata completeness: All 6 scored descriptive metadata groups are present. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

Cite this work

BibTeX

@article{allodium:10.1371/journal.pone.0361766,
  title = {Unveiling the neuroinflammatory potential of aspartame in Alzheimer’s disease: A comprehensive network toxicology and experimental validation approach},
  author = {Dongyang Li and Xuejun Weng and Yijuan Huang and Dongni Yang and Shunhan Yao and Weihao Zheng and Xiaohong Jiang and Yilin Wei and Sheng Xu and Chunwei Wei},
  year = {2026},
  journal = {PLOS One},
  doi = {10.1371/journal.pone.0361766},
  url = {https://doi.org/10.1371/journal.pone.0361766}
}

RIS

TY  - JOUR
TI  - Unveiling the neuroinflammatory potential of aspartame in Alzheimer’s disease: A comprehensive network toxicology and experimental validation approach
AU  - Dongyang Li
AU  - Xuejun Weng
AU  - Yijuan Huang
AU  - Dongni Yang
AU  - Shunhan Yao
AU  - Weihao Zheng
AU  - Xiaohong Jiang
AU  - Yilin Wei
AU  - Sheng Xu
AU  - Chunwei Wei
PY  - 2026
JO  - PLOS One
DO  - 10.1371/journal.pone.0361766
UR  - https://doi.org/10.1371/journal.pone.0361766
ER  -

APA

Li, D., Weng, X., Huang, Y., Yang, D., Yao, S., Zheng, W., Jiang, X., Wei, Y., Xu, S., & Wei, C. (2026). Unveiling the neuroinflammatory potential of aspartame in Alzheimer’s disease: A comprehensive network toxicology and experimental validation approach. PLOS One. https://doi.org/10.1371/journal.pone.0361766

Source records

crossref · retrieved 2026-11-04T23:48:47.528Z