Relative efficacy, safety and immunogenicity of bivalent versus monovalent COVID-19 mRNA booster vaccines: a randomized trial

Sufia Dadabhai, Taraz Samandari, Bo Zhang, Aaron Hudson, Nonhlanhla Mkhize, Asa Tapley, Jessica Andriesen, Penny Moore, Zvavahera Chirenje, Peter Elyanu, Joseph Makhema, Ethel Kamuti, Harriet Nuwagaba-Biribonwoha, Jin Kee, Jiani Hu, Katekani Baloyi-Oseh, Parth Shah, Kentse Khuto, Maurine Miner, Richard Lessells, Sinethemba Bhebhe, Tandile Modise, Haajira Kaldine, Azwidihwi Takalani, Margaret Yacovone, John Hural, Leigh Fisher, Craig Magaret, Florence Aweyo, Sharlaa Badal-Faesen, William Brumskine, Soritha Coetzer, Rodney Dawson, Sinead Delany-Moretlwe, Katherine Gill, Mina Hosseinipour, Steve Innes, Priya Kassim, Emmanuel Kafulafula, Fatima Laher, Nelly Mandona, Moelo Malahleha, Vongane Maluleke, Matsontso Mathebula, Grace Mboya, Essack Mitha, Kathy Mngadi, Pamela Mda, Tumelo Moloantoa, Nivashnee Naicker, Vimla Naicker, Annet Nanvubya, Maphoshane Nchabeleng, Walter Otieno, Elsje Potgieter, Disebo Potloane, Zelda Punt, Jamil Said, Yashna Singh, Mohammed Tayob, Deo Wabwire, Myron Cohen, M. Juliana McElrath, Erica Andersen-Nissen, Guido Ferrari, James Kublin, Linda Gail-Bekker, Peter Gilbert, Nyaradzo Mgodi, Philip Kotze, Yunda Huang, Nigel Garrett, Glenda Gray, Lawrence Corey

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DOI: 10.21203/rs.3.rs-10935317/v1
Published: 2026-09-14
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Publisher: Springer Science and Business Media LLC
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BibTeX

@article{allodium:10.21203/rs.3.rs-10935317/v1,
  title = {Relative efficacy, safety and immunogenicity of bivalent versus monovalent COVID-19 mRNA booster vaccines: a randomized trial},
  author = {Sufia Dadabhai and Taraz Samandari and Bo Zhang and Aaron Hudson and Nonhlanhla Mkhize and Asa Tapley and Jessica Andriesen and Penny Moore and Zvavahera Chirenje and Peter Elyanu and Joseph Makhema and Ethel Kamuti and Harriet Nuwagaba-Biribonwoha and Jin Kee and Jiani Hu and Katekani Baloyi-Oseh and Parth Shah and Kentse Khuto and Maurine Miner and Richard Lessells and Sinethemba Bhebhe and Tandile Modise and Haajira Kaldine and Azwidihwi Takalani and Margaret Yacovone and John Hural and Leigh Fisher and Craig Magaret and Florence Aweyo and Sharlaa Badal-Faesen and William Brumskine and Soritha Coetzer and Rodney Dawson and Sinead Delany-Moretlwe and Katherine Gill and Mina Hosseinipour and Steve Innes and Priya Kassim and Emmanuel Kafulafula and Fatima Laher and Nelly Mandona and Moelo Malahleha and Vongane Maluleke and Matsontso Mathebula and Grace Mboya and Essack Mitha and Kathy Mngadi and Pamela Mda and Tumelo Moloantoa and Nivashnee Naicker and Vimla Naicker and Annet Nanvubya and Maphoshane Nchabeleng and Walter Otieno and Elsje Potgieter and Disebo Potloane and Zelda Punt and Jamil Said and Yashna Singh and Mohammed Tayob and Deo Wabwire and Myron Cohen and M. Juliana McElrath and Erica Andersen-Nissen and Guido Ferrari and James Kublin and Linda Gail-Bekker and Peter Gilbert and Nyaradzo Mgodi and Philip Kotze and Yunda Huang and Nigel Garrett and Glenda Gray and Lawrence Corey},
  year = {2026},
  doi = {10.21203/rs.3.rs-10935317/v1},
  url = {https://doi.org/10.21203/rs.3.rs-10935317/v1}
}

RIS

TY  - JOUR
TI  - Relative efficacy, safety and immunogenicity of bivalent versus monovalent COVID-19 mRNA booster vaccines: a randomized trial
AU  - Sufia Dadabhai
AU  - Taraz Samandari
AU  - Bo Zhang
AU  - Aaron Hudson
AU  - Nonhlanhla Mkhize
AU  - Asa Tapley
AU  - Jessica Andriesen
AU  - Penny Moore
AU  - Zvavahera Chirenje
AU  - Peter Elyanu
AU  - Joseph Makhema
AU  - Ethel Kamuti
AU  - Harriet Nuwagaba-Biribonwoha
AU  - Jin Kee
AU  - Jiani Hu
AU  - Katekani Baloyi-Oseh
AU  - Parth Shah
AU  - Kentse Khuto
AU  - Maurine Miner
AU  - Richard Lessells
AU  - Sinethemba Bhebhe
AU  - Tandile Modise
AU  - Haajira Kaldine
AU  - Azwidihwi Takalani
AU  - Margaret Yacovone
AU  - John Hural
AU  - Leigh Fisher
AU  - Craig Magaret
AU  - Florence Aweyo
AU  - Sharlaa Badal-Faesen
AU  - William Brumskine
AU  - Soritha Coetzer
AU  - Rodney Dawson
AU  - Sinead Delany-Moretlwe
AU  - Katherine Gill
AU  - Mina Hosseinipour
AU  - Steve Innes
AU  - Priya Kassim
AU  - Emmanuel Kafulafula
AU  - Fatima Laher
AU  - Nelly Mandona
AU  - Moelo Malahleha
AU  - Vongane Maluleke
AU  - Matsontso Mathebula
AU  - Grace Mboya
AU  - Essack Mitha
AU  - Kathy Mngadi
AU  - Pamela Mda
AU  - Tumelo Moloantoa
AU  - Nivashnee Naicker
AU  - Vimla Naicker
AU  - Annet Nanvubya
AU  - Maphoshane Nchabeleng
AU  - Walter Otieno
AU  - Elsje Potgieter
AU  - Disebo Potloane
AU  - Zelda Punt
AU  - Jamil Said
AU  - Yashna Singh
AU  - Mohammed Tayob
AU  - Deo Wabwire
AU  - Myron Cohen
AU  - M. Juliana McElrath
AU  - Erica Andersen-Nissen
AU  - Guido Ferrari
AU  - James Kublin
AU  - Linda Gail-Bekker
AU  - Peter Gilbert
AU  - Nyaradzo Mgodi
AU  - Philip Kotze
AU  - Yunda Huang
AU  - Nigel Garrett
AU  - Glenda Gray
AU  - Lawrence Corey
PY  - 2026
DO  - 10.21203/rs.3.rs-10935317/v1
UR  - https://doi.org/10.21203/rs.3.rs-10935317/v1
ER  -

APA

Dadabhai, S., Samandari, T., Zhang, B., Hudson, A., Mkhize, N., Tapley, A., Andriesen, J., Moore, P., Chirenje, Z., Elyanu, P., Makhema, J., Kamuti, E., Nuwagaba-Biribonwoha, H., Kee, J., Hu, J., Baloyi-Oseh, K., Shah, P., Khuto, K., Miner, M., Lessells, R., Bhebhe, S., Modise, T., Kaldine, H., Takalani, A., Yacovone, M., Hural, J., Fisher, L., Magaret, C., Aweyo, F., Badal-Faesen, S., Brumskine, W., Coetzer, S., Dawson, R., Delany-Moretlwe, S., Gill, K., Hosseinipour, M., Innes, S., Kassim, P., Kafulafula, E., Laher, F., Mandona, N., Malahleha, M., Maluleke, V., Mathebula, M., Mboya, G., Mitha, E., Mngadi, K., Mda, P., Moloantoa, T., Naicker, N., Naicker, V., Nanvubya, A., Nchabeleng, M., Otieno, W., Potgieter, E., Potloane, D., Punt, Z., Said, J., Singh, Y., Tayob, M., Wabwire, D., Cohen, M., McElrath, M. J., Andersen-Nissen, E., Ferrari, G., Kublin, J., Gail-Bekker, L., Gilbert, P., Mgodi, N., Kotze, P., Huang, Y., Garrett, N., Gray, G., & Corey, L. (2026). Relative efficacy, safety and immunogenicity of bivalent versus monovalent COVID-19 mRNA booster vaccines: a randomized trial. https://doi.org/10.21203/rs.3.rs-10935317/v1

Source records

crossref · retrieved 2026-09-25T22:30:28.560Z