Downsizing a BTK PROTAC yields a G-loop independent molecular glue that blurs the boundary between degrader classes

Jin Wang, Ran Cheng, Hanfeng Lin, Lukáš Maršálek, Deepak Pathak, Xin Yu, Shrilekha Misra, Andrew Mitchell, Jennifer Woyach, Yang Gao, Xiaoli Qi

Open source

DOI: 10.21203/rs.3.rs-11296825/v1
Published: 2026-11-06
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Publisher: Springer Science and Business Media LLC
Open access: unknown

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Cite this work

BibTeX

@article{allodium:10.21203/rs.3.rs-11296825/v1,
  title = {Downsizing a BTK PROTAC yields a G-loop independent molecular glue that blurs the boundary between degrader classes},
  author = {Jin Wang and Ran Cheng and Hanfeng Lin and Lukáš Maršálek and Deepak Pathak and Xin Yu and Shrilekha Misra and Andrew Mitchell and Jennifer Woyach and Yang Gao and Xiaoli Qi},
  year = {2026},
  doi = {10.21203/rs.3.rs-11296825/v1},
  url = {https://doi.org/10.21203/rs.3.rs-11296825/v1}
}

RIS

TY  - JOUR
TI  - Downsizing a BTK PROTAC yields a G-loop independent molecular glue that blurs the boundary between degrader classes
AU  - Jin Wang
AU  - Ran Cheng
AU  - Hanfeng Lin
AU  - Lukáš Maršálek
AU  - Deepak Pathak
AU  - Xin Yu
AU  - Shrilekha Misra
AU  - Andrew Mitchell
AU  - Jennifer Woyach
AU  - Yang Gao
AU  - Xiaoli Qi
PY  - 2026
DO  - 10.21203/rs.3.rs-11296825/v1
UR  - https://doi.org/10.21203/rs.3.rs-11296825/v1
ER  -

APA

Wang, J., Cheng, R., Lin, H., Maršálek, L., Pathak, D., Yu, X., Misra, S., Mitchell, A., Woyach, J., Gao, Y., & Qi, X. (2026). Downsizing a BTK PROTAC yields a G-loop independent molecular glue that blurs the boundary between degrader classes. https://doi.org/10.21203/rs.3.rs-11296825/v1

Source records

crossref · retrieved 2026-11-10T13:55:32.500Z