Equipotent Doses and ED95 Extrapolation: Methodological Concerns in Trials of Ciprofol-Esketamine/Sufentanil for Elderly ESD [Response to Letter].

Qin X, Jiang H, Xie Y, Liu Q, Zhang Y, Mamtili I

DOI: 10.2147/dddt.s652138
Published: 2026
Container: Drug design, development and therapy
Publisher: Not recorded
Open access: yes

Credibility signals

limited evidence Score 45/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

cautionDOI registered: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
cautionDOI resolves: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
not scoredDirectory of Open Access Journals: No matching DOAJ record was present in this response. No allow-list match; this is not evidence of low credibility. Source: DOAJ; license: CC0
not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredROR affiliation: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
supportingOpen access status: Normalized open-access status: open. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
not scoredPublication license: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication version: A publication version was supplied but is not scored. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
cautionMetadata completeness: 5 of 6 scored descriptive metadata groups are present; missing fields increase uncertainty. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

Cite this work

BibTeX

@article{allodium:10.2147/dddt.s652138,
  title = {Equipotent Doses and ED95 Extrapolation: Methodological Concerns in Trials of Ciprofol-Esketamine/Sufentanil for Elderly ESD [Response to Letter].},
  author = {Qin X and Jiang H and Xie Y and Liu Q and Zhang Y and Mamtili I},
  year = {2026},
  journal = {Drug design, development and therapy},
  doi = {10.2147/dddt.s652138},
  url = {https://doi.org/10.2147/dddt.s652138}
}

RIS

TY  - JOUR
TI  - Equipotent Doses and ED95 Extrapolation: Methodological Concerns in Trials of Ciprofol-Esketamine/Sufentanil for Elderly ESD [Response to Letter].
AU  - Qin X
AU  - Jiang H
AU  - Xie Y
AU  - Liu Q
AU  - Zhang Y
AU  - Mamtili I
PY  - 2026
JO  - Drug design, development and therapy
DO  - 10.2147/dddt.s652138
UR  - https://doi.org/10.2147/dddt.s652138
ER  -

APA

X, Q., H, J., Y, X., Q, L., Y, Z., & I, M. (2026). Equipotent Doses and ED95 Extrapolation: Methodological Concerns in Trials of Ciprofol-Esketamine/Sufentanil for Elderly ESD [Response to Letter].. Drug design, development and therapy. https://doi.org/10.2147/dddt.s652138

Source records

pubmed · retrieved 2026-09-26T12:15:17.872Z