A Dual Mechanism-Based Physiologically Based Pharmacokinetic Model for Predicting Mitoxantrone and Liposomal Mitoxantrone Disposition: Preclinical Validation in Rats and Human Extrapolation with Clinical Evaluation

Yuxiang Xu, Shuo Li, Zhixuan Yang, Yushuo Qiu, Jiameng Dong, Xiaonan Gao, Jinglin Gao, Zhangying Feng, Mingxia Wang

Open source

DOI
10.2147/ijn.s638932
Published
2026-10
Container
International Journal of Nanomedicine
Publisher
Informa UK Limited
Open access
unknown

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BibTeX

@article{allodium:10.2147/ijn.s638932,
  title = {A Dual Mechanism-Based Physiologically Based Pharmacokinetic Model for Predicting Mitoxantrone and Liposomal Mitoxantrone Disposition: Preclinical Validation in Rats and Human Extrapolation with Clinical Evaluation},
  author = {Yuxiang Xu and Shuo Li and Zhixuan Yang and Yushuo Qiu and Jiameng Dong and Xiaonan Gao and Jinglin Gao and Zhangying Feng and Mingxia Wang},
  year = {2026},
  journal = {International Journal of Nanomedicine},
  doi = {10.2147/ijn.s638932},
  url = {https://doi.org/10.2147/ijn.s638932}
}

RIS

TY  - JOUR
TI  - A Dual Mechanism-Based Physiologically Based Pharmacokinetic Model for Predicting Mitoxantrone and Liposomal Mitoxantrone Disposition: Preclinical Validation in Rats and Human Extrapolation with Clinical Evaluation
AU  - Yuxiang Xu
AU  - Shuo Li
AU  - Zhixuan Yang
AU  - Yushuo Qiu
AU  - Jiameng Dong
AU  - Xiaonan Gao
AU  - Jinglin Gao
AU  - Zhangying Feng
AU  - Mingxia Wang
PY  - 2026
JO  - International Journal of Nanomedicine
DO  - 10.2147/ijn.s638932
UR  - https://doi.org/10.2147/ijn.s638932
ER  - 

APA

Xu, Y., Li, S., Yang, Z., Qiu, Y., Dong, J., Gao, X., Gao, J., Feng, Z., & Wang, M. (2026). A Dual Mechanism-Based Physiologically Based Pharmacokinetic Model for Predicting Mitoxantrone and Liposomal Mitoxantrone Disposition: Preclinical Validation in Rats and Human Extrapolation with Clinical Evaluation. International Journal of Nanomedicine. https://doi.org/10.2147/ijn.s638932

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