A Phase 2, Open-Label, Randomized Controlled Trial Evaluating Safety and Efficacy of Dose-Intensified Versus Standard Dosing Regimens of [ <sup>177</sup> Lu]Lu-PSMA-597 in mCRPC (OPTIMAL-PSMA)

Sobia Khan, Nathan Papa, Takanori Hioki, Megan Crumbaker, Sze-Ting Lee, Andrew Weickhardt, Shikha Sharma, Shraddha Weir, Katharina Luckerath, Edmond Kwan, Louise Emmett

Open source

DOI
10.2967/jnumed.126.272714
Published
2026-07-30
Container
Journal of Nuclear Medicine
Publisher
Society of Nuclear Medicine
Open access
unknown

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BibTeX

@article{allodium:10.2967/jnumed.126.272714,
  title = {A Phase 2, Open-Label, Randomized Controlled Trial Evaluating Safety and Efficacy of Dose-Intensified Versus Standard Dosing Regimens of [
                    <sup>177</sup>
                    Lu]Lu-PSMA-597 in mCRPC (OPTIMAL-PSMA)},
  author = {Sobia Khan and Nathan Papa and Takanori Hioki and Megan Crumbaker and Sze-Ting Lee and Andrew Weickhardt and Shikha Sharma and Shraddha Weir and Katharina Luckerath and Edmond Kwan and Louise Emmett},
  year = {2026},
  journal = {Journal of Nuclear Medicine},
  doi = {10.2967/jnumed.126.272714},
  url = {https://doi.org/10.2967/jnumed.126.272714}
}

RIS

TY  - JOUR
TI  - A Phase 2, Open-Label, Randomized Controlled Trial Evaluating Safety and Efficacy of Dose-Intensified Versus Standard Dosing Regimens of [
                    <sup>177</sup>
                    Lu]Lu-PSMA-597 in mCRPC (OPTIMAL-PSMA)
AU  - Sobia Khan
AU  - Nathan Papa
AU  - Takanori Hioki
AU  - Megan Crumbaker
AU  - Sze-Ting Lee
AU  - Andrew Weickhardt
AU  - Shikha Sharma
AU  - Shraddha Weir
AU  - Katharina Luckerath
AU  - Edmond Kwan
AU  - Louise Emmett
PY  - 2026
JO  - Journal of Nuclear Medicine
DO  - 10.2967/jnumed.126.272714
UR  - https://doi.org/10.2967/jnumed.126.272714
ER  - 

APA

Khan, S., Papa, N., Hioki, T., Crumbaker, M., Lee, S., Weickhardt, A., Sharma, S., Weir, S., Luckerath, K., Kwan, E., & Emmett, L. (2026). A Phase 2, Open-Label, Randomized Controlled Trial Evaluating Safety and Efficacy of Dose-Intensified Versus Standard Dosing Regimens of [ <sup>177</sup> Lu]Lu-PSMA-597 in mCRPC (OPTIMAL-PSMA). Journal of Nuclear Medicine. https://doi.org/10.2967/jnumed.126.272714

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