Scalable CAR-T production in a 2-litre perfusion stirred-tank bioreactor with automated harvesting and scale-down model characterisation

Pierre Springuel, Pedro Silva Couto, Dale J. Stibbs, Michal Szelwicki, Amanda Frangleton, Timo Schmidberger, Ajith George, Fern Slingsby, Nicola Bevan, Asma Ahmad, Rachel Legmann, Noushin Dianat, Rukmini Ladi, Julia Hengst, Qasim A. Rafiq

Open source

DOI
10.3389/fbioe.2025.1694134
Published
2026-01-12
Container
Frontiers in Bioengineering and Biotechnology
Publisher
Frontiers Media SA
Open access
unknown

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BibTeX

@article{allodium:10.3389/fbioe.2025.1694134,
  title = {Scalable CAR-T production in a 2-litre perfusion stirred-tank bioreactor with automated harvesting and scale-down model characterisation},
  author = {Pierre Springuel and Pedro Silva Couto and Dale J. Stibbs and Michal Szelwicki and Amanda Frangleton and Timo Schmidberger and Ajith George and Fern Slingsby and Nicola Bevan and Asma Ahmad and Rachel Legmann and Noushin Dianat and Rukmini Ladi and Julia Hengst and Qasim A. Rafiq},
  year = {2026},
  journal = {Frontiers in Bioengineering and Biotechnology},
  doi = {10.3389/fbioe.2025.1694134},
  url = {https://doi.org/10.3389/fbioe.2025.1694134}
}

RIS

TY  - JOUR
TI  - Scalable CAR-T production in a 2-litre perfusion stirred-tank bioreactor with automated harvesting and scale-down model characterisation
AU  - Pierre Springuel
AU  - Pedro Silva Couto
AU  - Dale J. Stibbs
AU  - Michal Szelwicki
AU  - Amanda Frangleton
AU  - Timo Schmidberger
AU  - Ajith George
AU  - Fern Slingsby
AU  - Nicola Bevan
AU  - Asma Ahmad
AU  - Rachel Legmann
AU  - Noushin Dianat
AU  - Rukmini Ladi
AU  - Julia Hengst
AU  - Qasim A. Rafiq
PY  - 2026
JO  - Frontiers in Bioengineering and Biotechnology
DO  - 10.3389/fbioe.2025.1694134
UR  - https://doi.org/10.3389/fbioe.2025.1694134
ER  - 

APA

Springuel, P., Couto, P. S., Stibbs, D. J., Szelwicki, M., Frangleton, A., Schmidberger, T., George, A., Slingsby, F., Bevan, N., Ahmad, A., Legmann, R., Dianat, N., Ladi, R., Hengst, J., & Rafiq, Q. A. (2026). Scalable CAR-T production in a 2-litre perfusion stirred-tank bioreactor with automated harvesting and scale-down model characterisation. Frontiers in Bioengineering and Biotechnology. https://doi.org/10.3389/fbioe.2025.1694134

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