Engineering ex vivo T-cell expansion for CAR-T therapy: bridging biological fidelity and bioprocess scalability through platforms, functional consumables, and integrated closed manufacturing

Qingzhi Wu, Menghui Jiang, Yuanyuan Li, Hui Huo, Haoyuan Cheng, Tian Jia, Yushu Wang, Ziwei Wang, Mengdie Ji, Jingjing Lin, Deyue Jiang, Nuo Zhang, Fuliang Chen

Open source

DOI
10.3389/fimmu.2026.1981337
Published
2026-10-20
Container
Frontiers in Immunology
Publisher
Frontiers Media SA
Open access
unknown

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BibTeX

@article{allodium:10.3389/fimmu.2026.1981337,
  title = {Engineering ex vivo T-cell expansion for CAR-T therapy: bridging biological fidelity and bioprocess scalability through platforms, functional consumables, and integrated closed manufacturing},
  author = {Qingzhi Wu and Menghui Jiang and Yuanyuan Li and Hui Huo and Haoyuan Cheng and Tian Jia and Yushu Wang and Ziwei Wang and Mengdie Ji and Jingjing Lin and Deyue Jiang and Nuo Zhang and Fuliang Chen},
  year = {2026},
  journal = {Frontiers in Immunology},
  doi = {10.3389/fimmu.2026.1981337},
  url = {https://doi.org/10.3389/fimmu.2026.1981337}
}

RIS

TY  - JOUR
TI  - Engineering ex vivo T-cell expansion for CAR-T therapy: bridging biological fidelity and bioprocess scalability through platforms, functional consumables, and integrated closed manufacturing
AU  - Qingzhi Wu
AU  - Menghui Jiang
AU  - Yuanyuan Li
AU  - Hui Huo
AU  - Haoyuan Cheng
AU  - Tian Jia
AU  - Yushu Wang
AU  - Ziwei Wang
AU  - Mengdie Ji
AU  - Jingjing Lin
AU  - Deyue Jiang
AU  - Nuo Zhang
AU  - Fuliang Chen
PY  - 2026
JO  - Frontiers in Immunology
DO  - 10.3389/fimmu.2026.1981337
UR  - https://doi.org/10.3389/fimmu.2026.1981337
ER  - 

APA

Wu, Q., Jiang, M., Li, Y., Huo, H., Cheng, H., Jia, T., Wang, Y., Wang, Z., Ji, M., Lin, J., Jiang, D., Zhang, N., & Chen, F. (2026). Engineering ex vivo T-cell expansion for CAR-T therapy: bridging biological fidelity and bioprocess scalability through platforms, functional consumables, and integrated closed manufacturing. Frontiers in Immunology. https://doi.org/10.3389/fimmu.2026.1981337

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