Case Report: Homozygous KISS1R mutation associated with congenital hypogonadotropic hypogonadism in two siblings: pulsatile GnRH therapy restores pituitary architecture and induces pubertal development

Rongwan Sun, Xiaotian Lei, Guiliang Peng, Jing Zhu, Liu Chen, Min Long

Open source

DOI: 10.3389/fmed.2026.1821097
Published: 2026-04-30
Container: Frontiers in Medicine
Publisher: Frontiers Media SA
Open access: unknown

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Cite this work

BibTeX

@article{allodium:10.3389/fmed.2026.1821097,
  title = {Case Report: Homozygous KISS1R mutation associated with congenital hypogonadotropic hypogonadism in two siblings: pulsatile GnRH therapy restores pituitary architecture and induces pubertal development},
  author = {Rongwan Sun and Xiaotian Lei and Guiliang Peng and Jing Zhu and Liu Chen and Min Long},
  year = {2026},
  journal = {Frontiers in Medicine},
  doi = {10.3389/fmed.2026.1821097},
  url = {https://doi.org/10.3389/fmed.2026.1821097}
}

RIS

TY  - JOUR
TI  - Case Report: Homozygous KISS1R mutation associated with congenital hypogonadotropic hypogonadism in two siblings: pulsatile GnRH therapy restores pituitary architecture and induces pubertal development
AU  - Rongwan Sun
AU  - Xiaotian Lei
AU  - Guiliang Peng
AU  - Jing Zhu
AU  - Liu Chen
AU  - Min Long
PY  - 2026
JO  - Frontiers in Medicine
DO  - 10.3389/fmed.2026.1821097
UR  - https://doi.org/10.3389/fmed.2026.1821097
ER  -

APA

Sun, R., Lei, X., Peng, G., Zhu, J., Chen, L., & Long, M. (2026). Case Report: Homozygous KISS1R mutation associated with congenital hypogonadotropic hypogonadism in two siblings: pulsatile GnRH therapy restores pituitary architecture and induces pubertal development. Frontiers in Medicine. https://doi.org/10.3389/fmed.2026.1821097

Source records

crossref · retrieved 2026-09-25T10:04:38.482Z